Japanese
Title頭部SPECT画像評価に関する基礎的研究 : 脳の構造とその変化がSPECT像へ及ぼす影響
Subtitle原著
Authors螻眞弘*, 駒谷昭夫*
Authors(kana)
Organization*山形大学医学部放射線医学講座
Journal核医学
Volume29
Number12
Page1455-1462
Year/Month1992/12
Article原著
Publisher日本核医学会
Abstract「要旨」頭部SPECTにおいて, 散乱線や低分解能が画像に及ぼす影響をファントム実験により評価し, 読影上の留意点を整理した. 6分割型円筒ファントムによるSPECT値の放射能濃度に対する直線性, および虚血巣を想定した局所的放射能低下の程度に対する直線性は, いずれも良好であったが, 低濃度になるほど散乱線の占める割合が大きくなった. 頭部ファントムによる白質対灰白質の比も低いほど散乱線の影響が顕著になった. また, 皮質の見かけ上の厚さがFWHMの2倍(17mm)以下では薄くなるにつれSPECT値が低下し, 8〜9mmでSPECT値は1/2になった. 脳溝の拡大した萎縮脳を想定して自作した髄液・脳実質容積比ファントムにより, 脳実質の占める割合に応じてSPECT値は正比例することを確認した. 頭部SPECT像の集積低下は, 脳組織の構造にも大きく左右されるので, X-CTやMR等の形態情報との対比による読影が重要である.
Practice臨床医学:一般
KeywordsSPECT, Phantom study, Brain.
English
TitleEffect of Scattering and Spatial Resolution on SPECT Quantification Values : Experimental Study Using Phantoms and Clinical Application
SubtitleOriginal Articles
AuthorsMasahiro KERA, Akio KOMATANI
Authors(kana)
OrganizationDepartment of Radiology, Yamagata University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume29
Number12
Page1455-1462
Year/Month1992/12
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]The relative SPECT values are often inaccurate by the scattering and limited spatial resolution of single photon emission CT (SPECT). These effects were studied using phantoms and some attentions on clinical application were investigated. Using cyrindrical phantom divided into six compartments filled with various radioactivities, the linear correlation between SPECT value and radioactivity, and also correlation with partial reduction of radioactivity were identified. But the SPECT value was relatively increased in proportion to the reduction of radioactivity due to the increase of scattering contribution. The SPECT value represented lower radioactivity when the cortical thickness was smaller than two times of FWHM and represented half radioactivity when the cortical thickness was equal to FWHM. Excellent correlation between SPECT value and radioactive partial volume averaging of brain with CSF was recognized using our handmade phantom simulating various degree of atrophic brain. It is very important to compare SPECT image with X-CT or MR image to avoid misreading taking the above mentioned effects due to scattering and limited spatial resolution.
PracticeClinical medicine
KeywordsSPECT, Phantom study, Brain.

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