| Japanese |
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| Title | 梗塞心筋のviability評価に対する18F-フルオロデオキシグルコース・ポジトロンCTの有用性 |
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| Subtitle | 原著 |
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| Authors | 庭山博行*, 吉田勝哉*, 増田善昭*, 稲垣義明* |
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| Organization | *千葉大学医学部第三内科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 11 |
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| Page | 1341-1352 |
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| Year/Month | 1992/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」陳旧性心筋梗塞患者18例に対し, 空腹時(6時間以上絶食後), 糖負荷時(50gブドウ糖経口負荷)FDG-PETを施行した. 空腹時画像は, 健常部心筋のFDG取り込みが抑制される群(A群12例)と抑制されない群(B群6例)の二つに分けられ, B群ではA群に比し血清遊離脂肪酸値が有意に低かった. 以上のうち7例を対象に冠状動脈形成術を施行し, 術前のFDG取り込みの程度と3か月後の壁運動異常改善の関係をみた. 糖負荷時画像でも空腹時画像でも, 心腔の血液プールからはっきりと心筋が分離できる程度にFDGの取り込みが見られれば, 術後高率に壁運動の改善がみられた(糖負荷時11/13セグメント, 空腹時6/8セグメント). 心筋のviability判定にFDG-PET画像は有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 18F-fluorodeoxyglucose, Positron emission tomography, Glucose-loaded state, Fasted state, Myocardial viability. |
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| English |
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| Title | Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography for Evaluating Myocardial Viability in old Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Hiroyuki NIWAYAMA, Katsuya YOSHIDA, Yoshiaki MASUDA, Yoshiaki INAGAKI |
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| Authors(kana) | |
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| Organization | Third Department of Internal Medicine, Chiba University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 11 |
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| Page | 1341-1352 |
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| Year/Month | 1992/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]The purpose of this study is to compare the characteristics of images obtained by positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) in the fasted state (>6 hours) and in the glucose-loaded state (oral 50g glucose load). In the both condition FDG-PET were performed in 18 cases with old myocardial infarction. PET images in the fasted state were divided into 2 groups (Group A; 12 cases and Group B; 6 cases). FDG uptake of normal region was visually absent (grade 0) in group A, whereas it was visually apparent (grade 1-3) in group B. Serum free fatty acid in group B was significantly lower than that in group A. In the 7 cases, the relation between myocardial FDG uptake of the infarcted regions and reversibility after coronary intervention was studied. Both in the fasted and in the glucose-loaded state, postoperative improvement was observed in the segments, in which myocardial uptake of FDG were visually apparent (glucose-loaded state, 11/13 segments; fasted state, 6/8 segments). Therefore FDG-PET images appeared to be useful for evaluating myocardial viability. |
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| Practice | Clinical medicine |
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| Keywords | 18F-fluorodeoxyglucose, Positron emission tomography, Glucose-loaded state, Fasted state, Myocardial viability. |
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