Japanese
Title慢性閉塞性肺疾患における肺血流シンチグラムと肺機能
Subtitle原著
Authors内田耕*, 足高毅*, 内堀繁康*, 高野政明**
Authors(kana)
Organization*東邦大学第二内科, **東邦大学大森病院中央放射線RI診断部
Journal核医学
Volume29
Number11
Page1325-1330
Year/Month1992/11
Article原著
Publisher日本核医学会
Abstract「要旨」慢性閉塞性肺疾患患者21名, 健常成人男子6名に換気血流シンチグラムおよび肺機能検査を施行した. 133Xe肺容量像は再呼吸相のカウントを加算して作製し, その関心領域は, 肺輪郭を表すようにカットオフレベルを約30%に設定して求め, その面積をLとした. 99mTc-MAA血流像の関心領域はカットオフレベルを50%, 70%, 90%に設定して求め, その面積をおのおのP50, P70, P90とし, PおよびP/Lと肺機能との関係を調べた. P/LはPに比して, より多くの肺機能指標と有意な相関があった, カットオフレベル50%, 70%, 90%で比較すると, P70/LがPaO2, 肺拡散能, 1秒量, %肺活量, 残気率など最も多くの肺機能指標と有意な相関があり, 肺気腫に伴う肺血流障害を反映しているものと考えられた.
Practice臨床医学:一般
Keywords99mTc-macroaggregate, 133Xe gas, Semiquantitative analysis of pulmonary perfusion, Chronic obstructive pulmonary disease, Pulmonary functions.
English
TitleCorrelation of the Perfusion Scintigram with Pulmonary Functions in Chronic Obstructive Pulmonary Disease
SubtitleOriginal Articles
AuthorsKou UCHIDA*, Tsuyoshi ASHITAKA*, Shigeyasu UCHIBORI*, Masaaki TAKANO**
Authors(kana)
Organization*Second Department of Internal Medicine, Toho University School of Medicine, **Department of Radiology, Toho University Hospital
JournalThe Japanese Journal of nuclear medicine
Volume29
Number11
Page1325-1330
Year/Month1992/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]We carried out ventilation-perfusion scintigraphy and pulmonary function tests in 21 patients with chronic obstructive pulmonary disease. We used 99mTc-macroaggregate for perfusion scintigram and 133Xe gas for ventilation scintigram. We added the radioactivities of rebreathing Phase and made lung volume image using computer. Regions of interest (ROIs) were derived from radioactivities in each image. ROIs on lung volume image included each whole lung and those on perfusion image included the areas which had relatively high radioactivity. We counted the area of ROIs on lung volume (L) and perfusion (P) images. Then we used the ratio of perfusion to lung volume (P/L) as a parameter of pulmonary perfusion. P/L had the significant correlations with the vital capacity, the actual FEV1.0, arterial oxygen partial pressure, diffusing capacity, RV/TLC and peak flow rate. These results suggested that P/L was a useful parameter of pulmonary perfusion in chronic obstructive pulmonary disease.
PracticeClinical medicine
Keywords99mTc-macroaggregate, 133Xe gas, Semiquantitative analysis of pulmonary perfusion, Chronic obstructive pulmonary disease, Pulmonary functions.

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