| Japanese |
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| Title | 虚血性心疾患の診断における高血圧性左室肥大の影響 - 運動負荷心筋シンチグラフィを用いて - |
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| Subtitle | 原著 |
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| Authors | 外山卓二*, 西村恒彦*, 植原敏勇*, 林田孝平*, 下永田剛*, 広瀬義晃*, 神長達郎*, 吉丸清道*, 野々木宏**, 土師一夫** |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部, **心臓内科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 11 |
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| Page | 1293-1298 |
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| Year/Month | 1992/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」高血圧による心筋肥大が虚血性心疾患の心筋虚血に与える影響について検討した. 対象は左前下行枝一枝障害の労作性狭心症患者64例(A群:高血圧(-)40例, B群:高血圧(+)心筋肥大(+)10例, C群:高血圧(+)心筋肥大(-)14例)である. 心筋肥大は心エコー図にて心室中隔または左室後壁が12mm以上とした. 運動負荷心筋シンチグラフィにて, タリウム陽性率(A群:88%, B群:60%, C群:93%), Defect score(A群:4.4±2.8, B群:2.7±3.6, C群:3.6±2.6)はB群でやや低い傾向があり, ST低下の頻度, 肺野タリウム集積率はやや高かった. 後側壁の洗い出し率はA群:46.7±7.1%, B群:36.2±5.7%, C群:45.6±11%であり, B群で有意に低値を示した. また心室中隔の後期摂取率から初期摂取率を引いた%RD(A群:11.7±8.6%, B群:5.2±7.9%, C群:5.7±5.3%)はA群に比しB群で低値を示した(P<0.05). しかし後側壁に対する心室中隔の洗い出し率の割合, 心室中隔の初期摂取率と後期摂取率には, 3群間に有意な差はなかった. 高血圧性心筋肥大の合併は非虚血部の洗い出し率の低下により, 虚血検出率を低下させる可能性がある. |
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| Practice | 臨床医学：一般 |
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| Keywords | Hypertension, Hypertrophy, Ischemic heart disease, Thallium myocardial scintigraphy. |
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| English |
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| Title | Influence of Hypertensive Left Ventricular Hypertrophy on Detection of Ischemic Area with Exercise Thallium-201 Myocardial Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Takuji TOYAMA*, Tsunehiko NISHIMURA*, Toshiisa UEHARA*, Kohei HAYASHIDA*, Tsuyoshi SHIMONAGATA*, Yoshiaki HIROSE*, Tatsuroh KAMINAGA*, Kiyomichi YOSHIMARU*, Hiroshi NONOGI**, Kazuo HAZE** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Cardiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 11 |
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| Page | 1293-1298 |
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| Year/Month | 1992/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Sixty-four patients with single left anterior descending artery disease having effort angina (group A: 40 patients without hypertension, group B: 10 patients with hypertrophic hypertension, group C: 14 patients with non-hypertrophic hypertension) were assessed the influence of hypertensive left ventricular (LV) hypertrophy on detection of ischemic area. The criterion of hypertrophy by two-dimensional echocardiography was > 12mm in the wall thickness of interventricular septal or posterior wall. Population in Group B might show low detectability in ischemic area by 201Tl myocardial scintigraphy (positive thallium rate 60%, defect score 2.7 +- 3.6), and high lung thallium uptake and high frequence of ECG positive among three groups. In semiquantitative analysis, the washout rate of the posterolateral wall and %RD (delayed %uptake-initial %uptake) of the septal wall in patients with Group B were lowest among three groups. However, the washout rate in the septal wall against the posterior wall, and the initial %uptake and the delayed %uptake of the septal wall were not significantly different among three groups. We could conclude that the decreased washout rate in nonischemic area with hypertensive LV hypertrophy might make the ischemic area masked. |
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| Practice | Clinical medicine |
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| Keywords | Hypertension, Hypertrophy, Ischemic heart disease, Thallium myocardial scintigraphy. |
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