Japanese
Titleタリウム運動負荷試験よりみた無症候性心筋虚血の検討
Subtitle原著
Authors松尾仁司*, 渡辺佐知郎*, 西田佳雄*, 加納素夫*, 松原徹夫*, 杉山明*, 松野由紀彦*, 小田寛*, 琴尾泰典*, 大橋宏重*, 後藤明**, 牧田一成**, 渡辺浩志**, 三宅浩**, 石黒源之***
Authors(kana)
Organization*県立岐阜病院循環器科・腎臓科, **放射線診断部, ***平野総合病院内科
Journal核医学
Volume29
Number11
Page1269-1276
Year/Month1992/11
Article原著
Publisher日本核医学会
Abstract「要旨」安静時心電図において, 異常Q波, 左室肥大, 脚ブロックを有さず, かつ負荷検査時冠動脈に75%以上の有意狭窄を有する連続100例の運動負荷タリウム心筋シンチグラフィ所見を検討し, 無症候性心筋虚血の頻度と特徴を明らかにした. 胸痛を呈した症例は33例, 心電図上虚血陽性者は43例, タリウム上虚血陽性は65例であった. 24例においては症候上, 心電図上, シンチ上においても虚血は認められなかった. 無症候性心筋虚血を呈する43例中20例は心電図上有意な変化は認められずシンチ所見上においてのみ虚血と判定された. 有痛性心筋虚血群と心電図陽性無痛性心筋虚血群, シンチ陽性心電図陰性無痛性心筋虚血群では, 糖尿病等の冠危険因子, 心筋梗塞既往の有無に有意差はなかった. 負荷量は有痛群で有意に低かったが, シンチグラフィ上虚血の範囲, 重症度に3群間に有意差は認めず, 虚血の検出には負荷心筋シンチグラフィが必要不可欠であることが示された.
Practice臨床医学:一般
KeywordsSilent myocardial ischemia, Stress thallium scintigraphy, Stress electrocardiography.
English
TitleThe Prevalence and the Clinical Characteristics of Silent Myocardial Ischemia Detected by Stress Thallium Scintigraphy
SubtitleOriginal Articles
AuthorsHitoshi MATSUO*, Sachiro WATANABE*, Yoshio NISHIDA*, Motoo KANOH*, Tetsuo MATSUBARA*, Akira SUGIYAMA*, Yukihiko MATSUNO*, Hiroshi ODA*, Yasunori KOTOO*, Hiroshige OOHASHI*, Akira GOTOH**, Kazunari MAKITA**, Hiroshi WATANABE**, Hiroshi MIYAKE**, Motoyuki ISHIGURO***
Authors(kana)
Organization*Division of Cardiology and Nephrology, **Division of Radiology, Prefectural Gifu Hospital, ***Department of Internal Medicine, Hirano General Hospital
JournalThe Japanese Journal of nuclear medicine
Volume29
Number11
Page1269-1276
Year/Month1992/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]The prevalence of silent myocardial ischemia was retrospectively assessed in a group of 100 consecutive patients with angiographically proved coronary artery disease, and diagnostic ECG, by symptom-limited exercise thallium-201 scintigraphy. Twenty-four patients had no evidence of ischemia despite adequate exercise level. So among 76 patients with exercise induced ischemia, only 33 patients (43%) stopped exercise due to anginal pain (symptomatic ischemia: Group 3). And 43 patients with asymptomatic ischemia composed of 23 patients (30%) with ECG change (Group 2B) and 20 patients (26%) without ECG change (Group 2A). Patients background including the history of old myocardial infarction and diabetes mellitus, were similar among Group 2A, 2B, and Group 3. And our major observation was that the extent and severity of quantified SPECT perfusion defects was nearly identical between 3 groups Thus in this study group, there was a rather high prevalence rate of silent ischemia (57%) by exercise thallium-201 criteria. Patients with silent ischemia, associated with positive and negative exercise ECG findings, and those with exercise angina had similar background and comparable amount of jeopardized myocardium.
PracticeClinical medicine
KeywordsSilent myocardial ischemia, Stress thallium scintigraphy, Stress electrocardiography.

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