Japanese
Title81mKr持続注入法と99mTc平衡時法を併用した新しい右室容積計測法
Subtitle原著
Authors木下信一郎*, 山下三朗*, 鈴木哲男*, 村松俊裕*, 井出雅生*, 鈴木成雄*, 土肥豊*, 西村克之**, 宮前達也**
Authors(kana)
Organization*埼玉医科大学第二内科, **放射線科
Journal核医学
Volume29
Number10
Page1185-1192
Year/Month1992/10
Article原著
Publisher日本核医学会
Abstract「要旨」99mTc心プール像併用81mKr持続注入法による新しい右室容積計測法を開発, 検討した. 半幾何学的カウント法によれば, Cv=voxel当たりのカウント, Cm=最大カウント, L=直角方向からみた容器最大長, d=pixel size, v=容積, Ct=総カウントとすると, Cv=Cm/(L/d), V=(Ct/Cv)×d3=(Ct/Cm)×L×d2となる. この原理を81mKr持続注入法の右室像へ適用した. ファントム実験では, 実測した容積と本法による容積はr=0.997(n=13, p<0.001)と高い相関を示した. 臨床的検討は, 81mKr持続注入下, 右前斜位から撮像し, 右室拡張終期(ED)像のCm, Ctを得, 99mTcによる心プール像の平衡時法ED像で右室最大径Lを測定した. これらの値から右室ED容積を得た. また心電図同期81mKr持続注入法から右室駆出率を求めた. 右室一回拍出量(SV)と熱希釈法のSVはr=0.90(n=14, p<0.001)の相関を示した. 本法は臨床的に使用し得る有用な右室容積計測法と考えられた.
Practice臨床医学：一般
KeywordsRight ventricular volume, Ventricular function, Krypton-81m, Radionuclide, Volumetry.
English
TitleRight Ventricular Volume Determination by Continuous 81mKr Infusion and 99mTc Blood Pool Imaging
SubtitleOriginal Articles
AuthorsShinichiro KINOSHITA*, Saburo YAMASHITA*, Tetsuo SUZUKI*, Toshihiro MURAMATSU*, Masao IDE*, Shigeo SUZUKI*, Yutaka DOHI*, Katsuyuki NISHIMURA**, Tatsuya MIYAMAE**
Authors(kana)
Organization*Second Department of Internal Medicine, Saitama Medical School, **Department of Radiology, Saitama Medical School
JournalThe Japanese Journal of nuclear medicine
Volume29
Number10
Page1185-1192
Year/Month1992/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]Our newly developed radionuclide method for the calculation of right ventricular (RV) volume was examined in this study. Using a semi-geometric count-based method, volume can be measured by the following equation: Cv=Cm/(L/d). V=(Ct/Cv)×d3=(Ct/Cm)×L×d2. (V=volume, Cv=voxel count, Cm=the maximum count of a container, Ct=the total count of the container, L=maximum length of the image of the container obtained from a direction perpendicular to the direction where the count data were collected, and d=pixel size.) A phantom study was performed by setting a cylindrical container in a system which circulated 5 liters of water per minute. 81mKr solution was infused continuously into the container, and images of the container were collected for one minute. Cm and Ct were obtained and, because the container was cylindrical, the maximum width of the image of the container was measured as L. The volume of the container was calculated using the above equation. The container's true volume and the volume measured by this method showed a good correlation with r=0.997 (n=13, p<0.001). This theorem was applied to RV images obtained in the 30 degree right anterior oblique position by continuous infusion of the 81mKr solution. Multiple gated acquisition was performed and RV end-diastolic maximum counts and total counts were obtained. The RV maximum width was measured as L on the end-diastolic cardiac pool image with 99mTc-D-HAS collected in the 40 degree left anterior oblique position. The values obtained from these two images were substituted in the above equation and the RV end-diastolic volume (RV-EDV) was calculated. The RV ejection fraction (RV-EF) was obtained from the 81mKr image. The RV stroke volume (SV) was calculated from multiplying the RV-EDV by the RV-EF. This value was compared to the SV with thermodilution. The correlation of these two values was r=0.90 (n=14, p<0.001). In conclusion, this new method for the calculation of RV volume was considered to be useful for both clinical and investigative purposes.
PracticeClinical medicine
KeywordsRight ventricular volume, Ventricular function, Krypton-81m, Radionuclide, Volumetry.

【全文PDF】