Japanese
Title三次元表示法による99mTc-MIBI心筋シンチグラム - 99mTc-MIBI SPECTおよび壁運動との比較検討 -
Subtitle技術報告
Authors鹿島田明夫*, 町田喜久雄*, 本田憲業*, 瀧島輝雄*, 間宮敏雄*, 高橋卓*, 釜野剛*, 村松正行*, 井上優介*, 伴隆一**
Authors(kana)
Organization*埼玉医科大学総合医療センター放射線科, **島津製作所
Journal核医学
Volume29
Number6
Page717-723
Year/Month1992/6
Article報告
Publisher日本核医学会
Abstract「要旨」16例の虚血性心疾患患者に対し三次元(3D)表示法による99mTc-MIBI心筋シンチグラムを施行し, 病変部位診断能について99mTc-MIBI SPECTとの比較検討を行った. 回転型ガンマカメラにより64方向の撮像を行い, 断層像はShepp-Logan filtered back projection法にて, 3D像はdepth-shading法にて再構成された. 読影は4人の放射線科医の合議により施行された. 3D像, SPECT像の病変部位診断能の敏感度, 特異度, 正確度には有意差はなく, またReceiver Operating Characteristic(ROC)解析にても両者に有意差はなかったが, 3D像はSPECTに比し血流欠損像の視覚判定が容易であると思われ, かつ一人の患者に対するデータ量を低減できることより, 三次元表示法は左室壁の血流欠損像の診断に有用であることが示唆された.
Practice臨床医学：一般
Keywords99mTc-MIBI myocardial scintigraphy, Three-dimensional display, SPECT.
English
TitleThree-Dimensional Display of 99mTc-MIBI Myocardial Scintigraphy
SubtitleTechnical Reports
AuthorsAkio KASHIMADA*, Kikuo MACHIDA*, Norinari HONDA*, Teruo TAKISHIMA*, Toshio MAMIYA*, Taku TAKAHASHI*, Tsuyoshi KAMANO*, Masayuki MURAMATSU*, Yusuke INOUE*, Ryuichi BAN**
Authors(kana)
Organization*Department of Radiology, Saitama Medical Center, Saitama Medical School, **Shimadzu Corporation
JournalThe Japanese Journal of nuclear medicine
Volume29
Number6
Page717-723
Year/Month1992/6
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]One of 99mTc-hexakis, 99mTc-methoxyisobutyl isonitrile (MIBI), has been demonstrated to have a myocardial uptake proportional to regional coronary blood flow. In this study, 99mTc-MIBI myocardial scintigraphy were performed for 16 patients with ischemic heart disease. After injection of 740 MBq of 99mTc-MIBI, 64 projection images were collected during a 360-degree rotation. Three-dimensional (3D) display of the left ventricle was reconstructed with depth-shading method from 99mTc-MIBI SPECT images, which were reconstructed by filtered back projection method. In 9 of the patients, left ventricular cineangiography were performed as diagnostic gold standard. Four physicians blinded to patients' clinical informations interpreted 3D images and SPECT images on separate occasions. Diagnosis of hypoperfusion by 3D displays agreed with those of SPECT in 92.9% (104/112 segments), and disagreed in 7.1% (8 segments). Sensitivity and specificity of 3D images were 87.0 and 93.9%, which were not statistically different (p<0.05) from that of SPECT images (91.3, 97.0%). Receiver operating characteristic (ROC) analysis revealed nearly identical curves for the two. Although 3D display had nearly identical diagnostic ability with SPECT, observers reported that 3D images were easier to diagnose than SPECT images. An advantage of the 3D display is that the display gives a more realistic impression of the left ventricle to an observer than tomography or planar imaging. Another advantage is that 3D display can reduce the amount of data storage compared with that of SPECT. In conclusion, 3D images may be useful for diagnosis of hypoperfusion of left ventricle.
PracticeClinical medicine
Keywords99mTc-MIBI myocardial scintigraphy, Three-dimensional display, SPECT.

【全文PDF】