| Japanese |
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| Title | 心拍同期99mTc-methoxy isobutyl isonitrile (MIBI) 画像の特性 |
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| Subtitle | 短報 |
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| Authors | 今井嘉門*, 西尾裕香里*, 荒木康史*, 斎藤頴*, 小沢友紀雄*, 八杉忠男*, 萩原和男**, 鎌田力三郎** |
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| Organization | *日本大学医学部第二内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 6 |
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| Page | 695-699 |
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| Year/Month | 1992/6 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」最近開発された冠灌流イメージ製剤99mTc-methoxy isobutyl isonitrile(MIBI)は比較的高エネルギーのγ線を放射するので, 心拍同期SPECTで拡張末期(ED)および収縮末期(ES)の画像を記録できる. この心拍同期MIBI画像の特性を解明するため, 非同期(NG)MIBI, タリウム(Tl)心筋シンチおよび左室壁運動とを心筋梗塞症6症例で対比検討した. 左室は8区画に細分し. 灌流および壁運動異常はおのおの, 0:正常, 1:軽度障害, 2:高度障害と評価し, 障害のseverityおよびextentのスコアーを求めた. Severityは壁運動:3.0±2.0(M±SD), Tl:3.3±1.7, NG-MIBI:3.7±1.3, ES-MIBI:5.0±0.6, ED-MIBI:7.3±2.0で, extentは壁運動:2.3±1.0, T1:2.5±1.3, NG-MIBI:3.0±1.6, ES-MIBI:3.5±0.8, ED-MIBI:4.8±1.0であった. 壁運動と比較して, ED-MIBIでのみseverityおよびextentは有意に大であつた. ED-MIBIは灌流障害を過大に評価するゆえ, 心拍同期画像を評価する際, 考慮すべき特徴である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Methoxy isobutyl isonitrile(MIBI), Perfusion imaging, Electrocardiogram gated image. |
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| English |
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| Title | Property of Electrocardiogram Gated Single Photon Emission Tomography by 99mTc-Methoxy Isobutyl Isonitrile |
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| Subtitle | Short Communications |
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| Authors | Kamon IMAI*, Yukari NISHIO*, Yasushi ARAKI*, Satoshi SAITO*, Yukio OZAWA*, Tadao YASUGI*, Kazuo HAGIWARA**, Rikisaburo KAMATA** |
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| Authors(kana) | |
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| Organization | *Second Department of Internal Medicine, **Department of Radiology, Nihon University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 6 |
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| Page | 695-699 |
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| Year/Month | 1992/6 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]99mTc-methoxy isobutyl isonitrile (MIBI) is a new developed myocardial perfusion imaging agent. Because this compound has higher photon energy than thallium (T1), electrocardiogram gated single photon emission tomography (SPECT): end-diastolic (ED) and end-systolic (ES) short axis (SA) images could be taken. To investigate property of gated MIBI SPECT, MIBI myocardial scintigraphy, Tl scintigraphy (TMS) and analysis of left ventricular wall motion were performed in 6 patients with myocardial infarction. Left ventricle was divided into 8 segments. Perfusion defect (PD) was scored: "0" (normal), "1" (hypo-perfusion), "2" (defect). Wall motion abnormality (WMA) was also scored: "0" (normo-kinesis), "1" (hypo-kinesis), "2" (a-, dys-kinesis). Severity and extent of PD and WMA were calculated. Severity of WMA was 3.0+-2.0 (M+-SD), severity of PD was 3.3+-1.7 in TMS, 3.7+-1.3 in no-gated MIBI, 5.0+-0.6 in ES-MIBI, 7.3+-2.0 in ED-MIBI. Extent of WMA was 2.3+-1.0. Extent of PD was 2.5+-1.3 in TMS, 3.0+-1.6 in no-gated MIBI, 3.5+-0.8 in ES-MIBI, 4.8+-1.0 in ED-MIBI. Compared with wall motion abnormality, severity and extent of PD in ED-MIBI was larger. From our data, it is concluded that perfusion defect in ED-MIBI was overestimated significantly. When we evaluate gated MIBI image, we must consider this property. |
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| Practice | Clinical medicine |
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| Keywords | Methoxy isobutyl isonitrile(MIBI), Perfusion imaging, Electrocardiogram gated image. |
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