| Japanese |
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| Title | FDG-PETを用いた消化器腫瘍性病変の評価 |
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| Subtitle | 短報 |
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| Authors | 福長徹*, 榎本和夫*, 岡住慎一*, 菊池俊之*, 山本宏*, 浅野武秀*, 磯野可一*, 有水昇**, 今関恵子**, 伊藤裕*** |
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| Authors(kana) | |
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| Organization | *千葉大学医学部第二外科, **放射線科, ***附属病院放射線部 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 6 |
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| Page | 687-690 |
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| Year/Month | 1992/6 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」腫瘍径2cm以上の消化器腫瘍性病変122例に対し18FDG PETを施行し, 良悪性鑑別診断における有用性を検討した. FDG静注投与後60分のstatic imageにおいて, 良性疾患17例中16例で正常組織と同等かそれ以下の集積であったが, 悪性腫瘍105例では肝細胞癌の一部を除き, FDGの強い集積を示した. FDG集積の指標として, 腫瘍部の放射能濃度と血漿中放射能濃度の比(Ci/Cp)を用い, Ci/Cp=2.0をcut off値として鑑別診断を試みたが, Ci/Cp≧2.0を示す90例中89例が悪性, Ci/Cp<2.0の32例中16例が良性, 15例が肝細胞癌であった. sensitivity 84.8%, specificity 94.1%, accuracyは86.1%であったが, これにはFDG非集積性の肝細胞癌の影響が大きく, これら肝細胞癌の一部を除きCi/Cpによる評価が消化器腫瘍性病変の良悪性鑑別診断に有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Positron emission tomography, 18F-fluorodeoxyglucose, Diagnostic imaging, Ci/Cp ratio. |
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| English |
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| Title | Evaluation of Gastroenterological Disease by Using 18F-FDG PET - Differential Diagnosis of Malignancy from Benignity - |
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| Subtitle | Short Communications |
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| Authors | Toru FUKUNAGA*, Kazuo ENOMOTO*, Shinichi OKAZUMI*, Toshiyuki KIKUCHI*, Hiroshi YAMAMOTO*, Takehide ASANO*, Kaichi ISONO*, Noboru ARIMIZU**, Keiko IMAZEKI**, Yutaka ITOH*** |
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| Authors(kana) | |
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| Organization | *Second Department of Surgery, Chiba University School of Medicine, **Department of Radiology, Chiba University School of Medicine, ***Central Division of Radiology, Chiba University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 6 |
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| Page | 687-690 |
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| Year/Month | 1992/6 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]In this study, we used 18F-FDG PET to differentiate gastroenterological malignancy from benignity. We investigated 122 patients with gastroenterological disease before treatment (with lesions exceeding 2.0 cm in diameter only). 60 min after injection of FDG, although 16 cases out of 17 benign disease did not reveal accumulation higher than normal tissue, 105 cases of malignant tumor except some of hepatocellular carcinoma revealed high accumulation of FDG. FDG uptake was expressed as the Ci/Cp ratio, calculated from radioactivity of the tumor (Ci) and the plasma (Cp). 89 cases out of 90 which show more than 2.0 of Ci/Cp ratio were malignant tumor. On the other hand, 32 cases which show less than 2.0 contained 16 cases of benign disease and 15 of hepatocellular carcinoma. FDG PET is a useful tool for differential diagnosis of malignant tumor from benign disease except some of hepatocellular carcinoma. |
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| Practice | Clinical medicine |
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| Keywords | Positron emission tomography, 18F-fluorodeoxyglucose, Diagnostic imaging, Ci/Cp ratio. |
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