| Japanese |
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| Title | 正常骨シンチグラフィにおける頭蓋骨の集積度の検討 |
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| Subtitle | 原著 |
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| Authors | 末松徹*, 吉田祥二*, 元原智文*, 藤原博文*, 西井博則*, 込山豊蔵*, 柳瀬正和*, 水谷正弘* |
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| Organization | *兵庫県立成人病センター放射線科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 5 |
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| Page | 599-605 |
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| Year/Month | 1992/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」正常骨シンチグラフィ282例(男性116例, 女性166例)について頭蓋冠の集積度を検討した. 頭蓋冠の集積度は頭蓋冠と大腿骨骨幹部のcontrast-to-noise ratioを基準に対比した. 男女おのおのを10歳代から80歳代までの8群, 計16群に分け, 性および年齢による有意差を検討した. 男女の有意差は30歳代で生じ始め(p<0.05), 80歳代まで女性の集積が有意に高かった. とくに50歳代と60歳代では男女差が顕著であった(p<0.001). 女性では20歳代に対して30歳代と40歳代では有意差はなかったが, 50歳代とでは危険率5%未満の有意差を認めた. また, 40歳代と50歳代, および30歳代と50歳代の間にも明らかな有意差がみられた(p<0.01). これに対し, 男性では各年齢群の間に有意な変化は認めなかった. 以上の結果より, 正常例における頭蓋冠の集積増加と閉経, すなわち卵巣機能低下あるいは停止との関連が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scintigraphy, Skull uptake, Hot skull, Osteoporosis, Menopause. |
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| English |
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| Title | Diffusely Increased Uptake in the Skull in Normal Bone Scans |
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| Subtitle | Original Articles |
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| Authors | Toru SUEMATSU, Shoji YOSHIDA, Tomofumi MOTOHARA, Hirofumi FUJIWARA, Hironori NISHII, Toyozo KOMIYAMA, Masakazu YANASE, Masahiro MIZUTANI |
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| Authors(kana) | |
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| Organization | Department of Radiology, Hyogo Medical Center for Adults |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 5 |
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| Page | 599-605 |
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| Year/Month | 1992/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Diffusely increased skull uptake (a hot skull) is often seen in patients with bone metastases and metabolic diseases. This finding is also, however, noticed in normal bone scans of aged women. To determine whether the hot skull could be considered a normal variant in elderly women and is associated to menopause, we studied 282 normal bone scans (166 women and 116 men without metabolic and hormonal disease; age range 11 to 84yr). We divided the patients into eight age groups-ages 10-19, 20-29, 30-39, 40-49, 50-59, 60-69, 70-79, and 80-89 yrs. Measurements of skull uptake were obtained from anterior total body views using contrast-to-noise ratio (CNR). CNR for the skull was calculated using the following equation: (counts skull-counts femur) / √counts skull+counts femur, where the denominator signifies a measure of the noise and the numerator represents the contrast between the skull and the midfemur. Counts skull and femur are the number of average counts per one pixel recorded over the skull and midfemur, respectively. The sex dependent difference in skull uptake began to develop in the age group 30-39 yrs (p<0.05). The skull showed greater activity in women than in men for age groups from 30-39 to 80-89yrs. In the age groups 50-59 and 60-69, the difference was particularly large (p<0.001). For women, the 50-59 yr age group had a significantly higher CNR than the 40-49 yr (p<0.01), 30-39 yr (p<0.05), and 20-29 yr age group (p<0.05). On the other hand, there was no significant difference between the 20-29 yr, 30-39 yr and 40-49 yr age groups. For men, the skull uptake was virtually unchanged with age. Our data strongly suggested that the hot skull in normal bone scan is related to menopausal estrogen deficiency. One should not necessarily regard it abnormal that elderly women suffer hot skull. |
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| Practice | Clinical medicine |
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| Keywords | Bone scintigraphy, Skull uptake, Hot skull, Osteoporosis, Menopause. |
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