Japanese
Title心プールシンチ法を用いた最大収縮期血圧-収縮末期容積関係の評価 : 観血的左室収縮性指標との比較検討
Subtitle原著
Authors山本朋彦*
Authors(kana)
Organization*新潟大学医学部内科学第一教室
Journal核医学
Volume29
Number2
Page233-242
Year/Month1992/2
Article原著
Publisher日本核医学会
Abstract「要旨」心プールシンチ法から計算した左室収縮末期容積と, カフ圧で測定した上腕動脈最大収縮期血圧から, 最大収縮期血圧-左室収縮末期容積関係の傾き(P/V slope)および最大収縮期血圧/左室収縮末期容積比(P/V ratio)を計算し, さらに心臓カテーテル検査法から求めた左室収縮性指標であるmean VCF, LVEF, ESVI, ESS/ESVIと比較し, P/V slopeおよびP/V ratioの有用性を検討した. 対象を心プールシンチと心臓カテーテル検査とを2週間以内に施行した12例とし, メトキサミン点滴静注により昇圧し, 3点で最大収縮期血圧と左室収縮末期容積を測定した後, その回帰直線の傾きをP/V slope, 昇圧前の最大収縮期血圧を左室収縮末期容積で除した値をP/V ratioとした. P/V slopeおよびP/V ratioは, mean VCF, LVEF, ESVIとは指数関数で, ESS/ESVIとは一次関数で, それぞれr=0.83〜0.88で回帰し, 非観血的な左室収縮性指標として有用であると考えられた.
Practice臨床医学：一般
KeywordsP/V slope, P/V ratio, Radionuclide ventriculography, Non-gated-SPECT, Left ventricular contractility.
English
TitleScintigraphic Evaluation of the Peak Systolic Pressure-End-Systolic Volume Relation : Comparison with Invasive Left Ventricular Contractile Indexes
SubtitleOriginal Articles
AuthorsTomohiko YAMAMOTO
Authors(kana)
OrganizationFirst Department of Internal Medicine, Niigata University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume29
Number2
Page233-242
Year/Month1992/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]We calculated the slope of peak systolic pressure-end-systolic volume relation (P/V slope) and the ratio of peak systolic pressure to end-systolic volume (P/V ratio) using radionuclide ventriculography and indirect sphygmomanometry to evaluate left ventricular contractility, and to assess the usefulness of these indexes, we compared them with mean VCF, LVEF, ESVI and ESS/ESVI using cardiac catheterization. Subjects were 12 patients who had received both radionuclide ventriculography and cardiac catheterization within a two weeks period. Left ventricular end-systolic volume and peak blood pressure were measured at 3 different points, one in the control state and the other two at two different hemodynamic states during infusion of Methoxamine. We defined P/V slope as the slope of the regression line of peak systolic pressure-end-systolic volume relation, and P/V ratio as the ratio of peak systolic pressure to left ventricular end-systolic volume at control. Left ventricular volume was measured by the non-gated-SPECT method and changes of the left ventricular volume was measured by the multigate method. P/V slope was correlated exponentially with mean VCF, LVEF and ESVI 0.34・e1.9X, r=0.86, p<0.001 for mean VCF; Y=0.25・e0.041X, r=0.83, p<0.001 for LVEF; y=7.8・e-0.028X, r=0.88, p<0.001 for ESVI), and correlated linearly with ESS/ESVI (y=1.6X-3.7, r=0.88, p<0.001). P/V ratio was also correlated exponentially with mean VCF, LVEF and ESVI 0.47・e1.4X, r=0.86, p<0.001 for mean VCF; Y=0.35・e0.032X, r=0.86, p<0.001 for LVEF; y=4.8・e-0.021X, r=0.87, p<0.001 for ESVI), and correlated linearly with ESS/ESVI (y=1.2X-2.6, r=0.83, p<0.001). We concluded that P/V slope and P/V ratio were useful indexes to evaluate left ventri-cular contractility noninvasively.
PracticeClinical medicine
KeywordsP/V slope, P/V ratio, Radionuclide ventriculography, Non-gated-SPECT, Left ventricular contractility.

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