| Japanese |
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| Title | 123I標識βメチル-p-ヨードフェニルペンタデカン酸による急性心筋梗塞の心筋イメージング - 201Tl心筋シンチグラフィ, 局所壁運動との比較 - |
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| Subtitle | 原著 |
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| Authors | 成瀬均*, 板野緑子*, 近藤誠宏*, 小亀孝夫*, 山本寿郎*, 森田雅人*, 川本日出雄*, 福武尚重*, 大柳光正*, 岩崎忠昭*, 福地稔** |
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| Organization | *兵庫医科大学第一内科, **核医学科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 1 |
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| Page | 77-84 |
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| Year/Month | 1992/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞11例に対して123I標識β-methyl-p-iodophenylpentadecanoic acid(BMIPP)による心筋イメージングを行い, 左室心筋を12segmentに分けて, 冠動脈造影(CAG), 塩化タリウム(201Tl)による心筋シンチグラフィ(TL), 断層心エコー図法による壁運動(WM)との比較を行った. 梗塞責任血管が左前下行枝近位部である症例におけるBMIPPの集積低下はすべてのsegmentに出現し得るが, 左前下行枝の一枝病変であるにもかかわらず, 心基部の下壁にも集積低下をきたす場合が3例あった. 亜急性期におけるBMIPPと同時に施行したTLはτ=0.82, p<0.001で相関があったが, BMIPP-TL間の乖離はTLよりBMIPPの欠損程度がより著明である症例が多かった. 乖離の症例においてその程度は急性期から回復期にかけてのWMの改善と関連がある可能性が示唆された. 亜急性期におけるBMIPPと同時期のWMの比較ではτ=0.50, p<0.001で相関があった. BMIPP-WM間の乖離はBMIPPの欠損が著明であるにもかかわらず, WMが比較的良好である場合に多く見られた. しかしながら, BMIPP, TL単独ではWMの改善と関連はなかった. 以上よりBMIPPはTLやWMとの組み合わせにより, 急性心筋梗塞において詳細な心筋の状態を評価するのに有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-β-methyl-p-iodophenyl-pentadecanoic acid, Acute myocardial infarction, Wall motion, 201Tl myocardial scintigraphy. |
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| English |
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| Title | Myocardial Imaging in Acute Myocardial Infarction Using β-Methyl-p-(123I)-Iodophenylpentadecanoic Acid : Comparison with 201Tl Imaging and Wall Motion |
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| Subtitle | Original Articles |
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| Authors | Hitoshi NARUSE*, Midoriko ITANO*, Tomohiro KONDO*, Takao KOGAME*, Juro YAMAMOTO*, Masato MORITA*, Hideo KAWAMOTO*, Naoshige FUKUTAKE*, Mitsumasa OHYANAGI*, Tadaaki IWASAKI*, Minoru FUKUCHI** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, **Department of Nuclear Medicine, Hyogo College of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 1 |
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| Page | 77-84 |
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| Year/Month | 1992/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Myocardial imaging using β-methyl-p-(123I)-iodophenylpentadecanoic acid (BMIPP) was performed in 11 patients with acute myocardial infarction. The left ventricular images were divided into 12 segments, and myocardial imagings with BMIPP were compared with coronary angiography (CAG), thallium-201 myocardial scintigraphy (TL) and wall motion obtained by two-dimensional echocardiography (WM). When the culprit lesion was at the proximal point of the left anterior descending artery (LAD), all segments showed depressed uptake. In 3 cases with single vessel disease of the LAD, inferior wall of the basis showed reduced uptake of BMIPP despite the location of the culprit lesion. In cases with discordant uptake between the two tracers, BMIPP frequently showed more severely depressed uptake than TL in the subacute phase, although the uptake of BMIPP correlated with that of TL (τ=0.82, p<0.001). In such cases, the discordance was related to the improvement in WM from the acute phase to the convalescent phase. BMIPP uptake correlated with WM in the subacute phase (τ=0.50, p<0.001). BMIPP showed more severely depressed uptake while WM showed mild asynergy in most cases in which discordance was found between the BMIPP and WM findings. However, there was no correlation between the change in WM from the acute to subacute phases, or the uptakes of BMIPP and TL alone. We concluded that the myocardial condition can be evaluated in detail in acute myocardial infarction by comparing the findings of BMIPP with those of TL and WM. |
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| Practice | Clinical medicine |
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| Keywords | 123I-β-methyl-p-iodophenyl-pentadecanoic acid, Acute myocardial infarction, Wall motion, 201Tl myocardial scintigraphy. |
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