| Japanese |
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| Title | 99mTc-MIBIを用いた運動負荷心筋シンチグラフィによる冠動脈病変診断 - 同時左室壁運動評価の有用性を含めて - |
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| Subtitle | 原著 |
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| Authors | 植原敏勇*, 西村恒彦*, 汲田伸一郎*, 下永田剛*, 林田孝平*, 片渕哲朗*, 岡尚嗣*, 土師一夫**, 野々木宏** |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部, **内科 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 1 |
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| Page | 49-58 |
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| Year/Month | 1992/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」近年開発された99mTc-MIBIは, 201TlClに代わる心筋製剤として注目されている. 今回本薬剤を臨床時に使用する機会を得たので, 運動負荷・安静時99mTc-MIBI心筋シンチグラフィの診断精度を同負荷にて施行した201TlCl運動負荷心筋シンチグラフィと比較検討した. 対象は, 冠動脈疾患27例である. 99mTc-MIBI心筋シンチグラフィはRCA, LCX領域の診断に有用で, Planar診断よりもSPECT診断が優れていた. また201TlClと違い, 再分布現象が存在せずwashout rateの算出ができないことに起因する多枝病変の検出能の低下は, 99mTc-MIBI静注時のファーストパス心プールシンチグラフィの施行により, 十分補えることが判明した. 結論として, 99mTc-MIBI運動負荷・安静時心筋シンチグラフィによる心機能・心筋灌流同時評価は, 201TlClよりも鮮明な心筋画像が得られ, かつ良好な診断精度が得られることが判明した. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MIBI, Exercise myocardial scintigraphy, Coronary heart disease, Left ventricular function. |
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| English |
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| Title | Diagnostic Accuracy of Coronary Artery Lesion by 99mTc-MIBI Exercise Myocardial Scintigraphy - Containing the Utility of Simultaneous Assessment of Left Ventricular Function - |
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| Subtitle | Original Articles |
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| Authors | Toshiisa UEHARA*, Tsunehiko NISHIMURA*, Shin-ichiro KUMITA*, Tsuyoshi SHIMONAGATA*, Kohei HAYASHIDA*, Tetsuro KATAFUCHI*, Hisashi OKA*, Kazuo HAZE**, Hiroshi NONOKI** |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, **Division of Cardiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 1 |
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| Page | 49-58 |
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| Year/Month | 1992/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To determine whether technetium-99m hexakis-2-methoxy isobutyl isonitrile (99mTc-MIBI) myocardial scintigraphy is a superior method in the detection of coronary artery disease, exercise and rest 99mTc-MIBI planar and SPECT scintigraphy were performed on 27 patients with coronary artery disease. When 99mTc-MIBI (555 MBq(15mCi)) was injected, first-pass radionuclide angiography (FPRNA) was simultaneously performed by a new mobile multicrystal gamma camera (SIM-400), and LV function (LVEF) was evaluated quantitatively. Visual semiquantitative detection of coronary lesions using 99mTc-MIBI images showed superior accuracy to that obtained using 201TlCl images. 99mTc-MIBI SPECT images were particularly useful in diagnosing LCX and RCA lesions. Moreover, the simultaneous assessment of perfusion and left ventricular function by 99mTc-MIBI FPRNA proved to be useful in the diagnosis of multi-vessel disease. In summary, 99mTc-MIBI SPECT scintigraphy with simultaneous assessment of left ventricular function showed better diagnostic accuracy than 201TlCl myocardial scintigraphy. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MIBI, Exercise myocardial scintigraphy, Coronary heart disease, Left ventricular function. |
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