| Japanese |
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| Title | 3検出器SPECT装置による上咽頭癌患者の頭蓋底骨浸潤の診断 |
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| Subtitle | 原著 |
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| Authors | 油井信春*, 戸川貴史*, 木下富士美*, 嶋田文之**, 秋山芳久*** |
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| Organization | *千葉県がんセンター核医学診療科, **頭頸科, ***物理室 |
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| Journal | 核医学 |
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| Volume | 29 |
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| Number | 1 |
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| Page | 37-47 |
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| Year/Month | 1992/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」3検出器SPECT装置(東芝GCA 9300A)を用いて頭蓋骨のSPECTを行った. fan-beam collimatorを装着したときの解像力は従来のカメラ回転SPECT装置に比して著しく向上し, 複雑な解剖学的構造を有する頭蓋, 顔面骨のすぐれたイメージを得ることができた. 12人の上咽頭癌患者に骨SPECTを施行し, CTにより骨浸潤の明らかな患者全3例で異常所見が得られたのみならず, CTなどの検査で骨異常がないと考えられていた5例でも異常が指摘でき, それらの患者の予後は悪かった. 頭蓋骨SPECTは上咽頭癌患者の頭蓋底骨浸潤を早期に検出できる可能性がある. 「I. はじめに」骨シンチグラフィは一般的に骨転移の早期検出に臨床的意義が集約されていると見なされているが, 少数ながら頭頸部腫瘍の骨浸潤にも有用であるとの報告もある. しかし下顎骨や上顎骨のような比較的顔面に近い骨の診断は可能であっても, 複雑な解剖学的構造を有する頭蓋底骨の深部の異常を検出するにはplanar像では困難である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scintigraphy, SPECT, Nasopharyngeal carcinoma, Skull base. |
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| English |
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| Title | Assessment of Skull Base Involvement of Nasopharyngeal Carcinoma by Bone SPECT Using Three Detectors System |
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| Subtitle | Original Articles |
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| Authors | Nobuharu YUI*, Takashi TOGAWA*, Fujimi KINOSHITA*, Fumiyuki SHIMADA**, Yoshihisa AKIYAMA*** |
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| Authors(kana) | |
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| Organization | *Division of Nuclear Medicine, **Division of Head and Neck Surgery, ***Division of Radiation Physics, Chiba Cancer Center Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 29 |
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| Number | 1 |
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| Page | 37-47 |
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| Year/Month | 1992/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]SPECT of the skull was performed on twelve patients with histologically proven nasopharyngeal carcinoma using newly developed three detectors SPECT system (Toshiba GCA 9300A) mounted with fan-beam collimators, for the purpose of early detection of skull base involvement of the disease. This SPECT system has extremely improved resolution with FWHM of 8 mm in the center, and it provides clear tomographic images of the skull which has anatomically complex structure. SPECT image was taken 3 hours after injection of 740 MBq (20 mCi) of 99mTc-MDP following whole body skeletal survey. In twelve patients with confirmed nasopharyngeal carcinoma, 8 patients showed positive findings on SPECT. Three of SPECT positive patients also showed destructive findings on CT. Other five positive patients did not show destructive findings on CT at their initial examinations, but in three of them CT findings turned to positive later. SPECT was superior to CT in early detection of skull base involvement. We believe that SPECT of the skull is a diagnostic tool for early detection of skull base involvement of nasopharyngeal carcinoma. |
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| Practice | Clinical medicine |
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| Keywords | Bone scintigraphy, SPECT, Nasopharyngeal carcinoma, Skull base. |
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