Japanese
Title原発性肺癌 (扁平上皮癌) におけるGa-67集積と放射線療法腫瘍縮小効果の関係
Subtitle原著
Authors東光太郎*, 高瀬秀子*, 関宏恭*, 大口学*, 興村哲郎*, 宮村利雄*, 山本達*, 力丸茂穂**
Authors(kana)
Organization*金沢医科大学放射線医学教室, **石川県立中央病院放射線科
Journal核医学
Volume29
Number1
Page9-15
Year/Month1992/1
Article原著
Publisher日本核医学会
Abstract「要旨」原発性肺癌(扁平上皮癌)におけるGa-67集積と放射線療法腫瘍縮小効果の関係について, 検討した. 16例の原発性肺癌(扁平上皮癌)を対象として, 未治療時の肺癌のGa-67集積度を測定し, 放射線療法腫瘍縮小効果(腫瘍縮小率)との間の相関関係について検討したところ, 両者の間には有意な負の相関関係が認められた(r=-0.701, P<-0.01). すなわち, Ga-67集積度の低い肺癌ほど放射線療法腫瘍縮小効果が大きい傾向があった. また, 放射線療法による腫瘍縮小率が50%以上の群のGa-67集積度は, 腫瘍縮小率50%未満の群のそれよりも有意に低値を示した(p<0.02). さらに, 分化度の低い原発性肺癌(扁平上皮癌)ほどGa-67集積度は低い傾向が認められた. これらの成績は, Ga-67集積度が原発性肺癌(扁平上皮癌)の放射線療法腫瘍縮小効果を予測する際の有用な指標となる可能性を示すと考えた.
Practice臨床医学:一般
KeywordsGa-67, Lung cancer, Squamous cell carcinoma, Radiation therapy, Tumor reduction ratio.
English
TitleRelationship between Ga-67 Uptake and Radiotherapeutic Response of Primary Lung Cancer (Squamous Cell Carcinoma)
SubtitleOriginal Articles
AuthorsKotaro HIGASHI*, Shuko TAKASE*, Manabu OHGUCHI*, Hiroyasu SEKI*, Tetsuro OKIMURA*, Toshio MIYAMURA*, Itaru YAMAMOTO*, Shigeho RIKIMARU**
Authors(kana)
Organization*Department of Radiology, Kanazawa Medical University, **Department of Radiology, Ishikawa Prefectural Central Hospital
JournalThe Japanese Journal of nuclear medicine
Volume29
Number1
Page9-15
Year/Month1992/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]This investigation was undertaken to evaluate the relationship between Ga-67 uptake and radiotherapeutic response of primary lung cancer (squamous cell carcinoma), Ga-67 uptake of tumor was estimated on 16 patients with untreated primary lung cancer (squamous cell carcinoma). Ga-67 uptake was then compared with the response to radiation therapy (tumor reduction ratio). There was statistically significant inverse correlation between Ga-67 uptake and response to radiation therapy (r=-0.701, p<0.01). The fewer the Ga-67 accumulation in the tumor, the more effective radiotherapy in reducing tumor size. In conclusion, Ga-67 scintigraphy appears to be able to predict the response of primary lung cancer (squamous cell carcinoma) to radiation therapy.
PracticeClinical medicine
KeywordsGa-67, Lung cancer, Squamous cell carcinoma, Radiation therapy, Tumor reduction ratio.

【全文PDF】