| Japanese |
|---|
| Title | 3検出器SPECTを用いた超早期イメージ (4〜6分) による123I-IMP脳血流測定 - 脳腫瘍症例を中心として - |
|---|
| Subtitle | ≪短報≫ |
|---|
| Authors | 石原眞木子*,†, 油井信春*, 戸川貴史*, 蓑島聡****, 内田佳孝***, 難波宏樹**, 木下富士美*, 小圷正木*, 有水昇**** |
|---|
| Authors(kana) | |
|---|
| Organization | *千葉県がんセンター核医学診療部, **脳神経外科, ***君津中央病院放射線科, ****千葉大学医学部放射線医学教室, †現帝京大学医学部附属市原病院放射線科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 28 |
|---|
| Number | 12 |
|---|
| Page | 1503-1507 |
|---|
| Year/Month | 1991/12 |
|---|
| Article | 報告 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」脳腫瘍症例に対し, 3検出器回転型SPECT装置を用いて123I-IMP静注後4〜6分の超早期像から腫瘍部の血流測定を行った. olfactory groove meningioma malignant astrocytomaの2例において, 超早期像ではMRI上の病巣に一致して正常脳皮質より著明に高い集積を認めたが, 早期像では集積は低下していた. 2例とも, 超早期像から求めた腫瘍部の血流量は正常脳皮質より高値を示した. 従来の早期像から補正する方法では, 病巣の血流量を正確に反映せず, 超早期像に基づく方法により腫瘍部の脳血流の増加が示し得たと考えられる. 「I. はじめに」N-Isopropyl-p-[123I]-Iodoamphetamine (以下IMPと略)による局所脳血流定量法は, 1982年Kuhlらがリング型SPECT装置を用いて初めて報告したものであるが, 通常のガンマカメラ回転型SPECT装置では, IMP静注5分後の撮像(以下超早期像と記す)をすることが難しい. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | 123I-IMP, SPECT, Blood flow, Brain tumor. |
|---|
| English |
|---|
| Title | Blood Flow Measurement of Brain Tumor by 123I-IMP Using 3-Heads Rotating Gamma Camera SPECT |
|---|
| Subtitle | |
|---|
| Authors | Makiko ISIHARA*, Nobuharu YUI*, Takashi TOGAWA*, Satoshi MINOSHIMA****, Yoshitaka UCHIDA***, Hiroki NAMBA**, Fujimi KINOSHITA*, Masaki KOAKUTSU*, Noboru ARIMIZU**** |
|---|
| Authors(kana) | |
|---|
| Organization | *Divisions of Nuclear Medicine, **Division of Neurosurgery, Chiba Cancer Center Hospital, *** Division Of Radiology, Kimitsu Chuoh Hospital, ****Department of Radiology, Chiba University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 28 |
|---|
| Number | 12 |
|---|
| Page | 1503-1507 |
|---|
| Year/Month | 1991/12 |
|---|
| Article | Report |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] Using 3-heads rotating gamma camera SPECT system, regional blood flow was measured from the super-early image obtained 4 to 6 minutes after the intravenous injection of 123I-IMP on 11 patients with various brain tumors. Two cases of olfactory groove meningioma and malignant astrocytoma showed significantly high 123I-IMP uptake by the lesion visualized by MRI compared to the uptake by normal brain cortex on super-early image but 123I-IMP uptake by the tumor decreased on early image. In both cases, blood flow of the tumor measured from super-early image showed values much higher than those of normal brain cortex. It was thought that usual correction method based on early image did not correctly represent the blood flow of the lesion but that the present method based on super-early image could show the increase of blood flow of the tumor. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | 123I-IMP, SPECT, Blood flow, Brain tumor. |
|---|