| Japanese |
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| Title | 123I-N-isopropyl-p-iodoamphetamine (IMP) の異常集積を経過観察し得た外傷性てんかんの一例 |
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| Subtitle | ≪症例報告≫ |
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| Authors | 永田保*,†, 多田村栄二*, 山田弘樹*, 天野隆*, 川嶌剛*, 服部昭*, 藤堂義郎*, 米倉義晴** |
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| Authors(kana) | |
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| Organization | *長浜赤十字病院放射線科, **京都大学医学部脳病態生理学講座, †現滋賀医科大学放射線科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1491-1495 |
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| Year/Month | 1991/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」本来機能的障害であるてんかんは, CT・MR等で異常を認めないことが多いが, 昨今その病態把握にIMPの有用性が報告されている. 今回われわれはIMPが異常集積した外傷性てんかんの一例を経験し, 症状の変化にともなうIMPの集積の変化を観察することができた. 症例は31歳男性で, 交通事故直後, CT上では異常を認めたが, その後CT上異常がハッキリしなくなるまで形態学上改善したにも関わらず, IMPによる脳血流SPECTの早期像および後期像にて左側頭頭頂葉に異常集積を認めた. この異常集積は, 早期像よりも後期像にて長期間持続し, IMPのretention機構の変化を示唆した. 「I. はじめに」123I標識-N-isopropyl-p-iodoamphetamine (IMP)による脳血流SPECTは, てんかんの焦点の検出や, その病態の検索に広く用いられている. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-IMP, Epilepsy, Head trauma. |
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| English |
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| Title | Follow Up Study in a Case of Traumatic Epilepsy with Increased Accumulation of 123I-N-Isopropyl-p-Iodoamphetamine |
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| Subtitle | |
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| Authors | Tamotsu NAGATA*,†, Hiroki YAMADA*, Eiji TADAMURA*, Takashi AMANO*, Tsuyoshi KAWASHIMA*, Akira HATTORI*, Giro TODO*, Yoshiharu YONEKURA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Nagahama Red Cross Hospital, **Department of Brain Pathophysiology, Kyoto University School of Medicine, †Department of Radiology, Shiga University of Medical Science |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1491-1495 |
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| Year/Month | 1991/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Recent studies suggested the potential use of 123I-N-isopropyl-p-iodoamphetamine (IMP) for the assessment of pathophysiology of epilepsy. We studied a case of epilepsy with increased accumulation of IMP. Brain SPECT scan of IMP was performed in a case of 31-year-old male with traumatic epilepsy. Increased accumulation of IMP was observed in the left temporal area on both early (20 min after injection) and delayed (3 hr) images of studied 6 weeks after the head trauma. X-CT did not show any abnormalities. The accumulation of IMP decreased as the symptom of the patient improved. The SPECT study performed 3 months after the accident showed slightly decreased uptake in the left temporal area on the early image with homogenous uptake in the delayed image. These findings suggested the altered retention mechanism of IMP in this case. |
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| Practice | Clinical medicine |
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| Keywords | 123I-IMP, Epilepsy, Head trauma. |
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