| Japanese |
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| Title | 201Tl SPECTによる膵癌診断 |
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| Subtitle | ≪原著≫ |
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| Authors | 戸川貴史*, 油井信春*, 木下富士美*, 小圷正木**, 竜崇正***, 山崎将人**** |
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| Authors(kana) | |
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| Organization | *千葉県がんセンター核医学診療部, **千葉県がんセンター核医学診療部 (現:茂原保健所), ***千葉県がんセンター消化器科, ****千葉大学医学部第二外科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1475-1481 |
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| Year/Month | 1991/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」膵癌, 十二指腸乳頭部癌10例, および慢性膵炎7例の計17例に対し, 3検出器回転型ガンマカメラ装置を用い201Tl SPECTを行った. 膵癌, 十二指腸乳頭部癌10例中7例においては, 病巣が201Tl SPECTにより明瞭に描出された. 30mm径の病巣が陽性描画されたのに対し, 80mm径でも描画できない症例があった. すなわち, 膵癌への201Tl集積には腫瘍の大きさよりも血流あるいは癌組織の分化度が関与していると考えられた. 慢性膵炎7例中5例では膵への201Tl集積がなく, 201Tl SPECTによる膵癌診断のsensitivityは70%, specificityは71%およびaccuracyは71%であった. 膵癌に対する有効なSPECT用イメージング製剤がない現状において, 今回の201Tl SPECTによる膵癌の評価は十分満足すべき結果と考えられ, 201Tl SPECTは膵腫瘤性病変の新しい診断法として期待される. |
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| Practice | 臨床医学：一般 |
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| Keywords | SPECT, 201Tl-chloride, Pancreatic cancer. |
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| English |
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| Title | Diagnosis of Pancreatic Cancer Using 201Tl-Chloride and a Three-Head Rotating Gamma Camera SPECT System |
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| Subtitle | - Original Articles - |
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| Authors | Takashi TOGAWA*, Nobuharu YUI*, Fujimi KINOSHITA*, Masaki KOAKUTSU**, Munemasa RYU***, Masato YAMAZAKI**** |
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| Authors(kana) | |
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| Organization | *Division of Nuclear Medicine, Chiba Cancer Center, **Mobara Public Health Center, ***Division of Gastroenterology, Chiba Cancer Center, ****Second Department of Surgery, Chiba University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1475-1481 |
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| Year/Month | 1991/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 201Tl SPECT was performed on 17 patients with pancreatic cancer or chronic pancreatitis using a three-head rotating gamma camera SPECT system. In 7 of 10 patients with pancreatic cancer, the lesions were clearly delineated by 201Tl SPECT. Whereas the lesion of 30 mm in diameter was visualized, a large tumor of 80 mm in diameter could not be visualized. Namely, it was thought that 201Tl uptake by pancreatic cancer might be well correlated with tumor blood flow and/or its histological subtype rather than with tumor size. In 5 of 7 patients with chronic pancreatitis, no uptake by the pancreas was shown. The sensitivity, specificity, and accuracy in diagnosing pancreatic cancer by 201Tl SPECT were 70%, 71%, and 71%, respectively. The present results obtained by 201Tl SPECT were thought satisfactory enough to evaluate pancreatic cancer under the present conditions where there was no useful imaging agent for visualizing pancreatic cancer by SPECT. 201Tl SPECT is expected to be a new diagnostic tool for investigation of pancreatic tumorous lesion. |
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| Practice | Clinical medicine |
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| Keywords | SPECT, 201Tl-chloride, Pancreatic cancer. |
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