| Japanese |
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| Title | 99mTc標識コロイドを用いた経動脈注入, 経門脈注入肝シンチグラフィ |
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| Subtitle | ≪原著≫ |
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| Authors | 井上優介*, 大嶽達*, 百瀬敏光*, 渡辺俊明*, 小坂昇*, 西川潤一*, 佐々木康人*, 沢田俊夫**, 武藤徹一郎** |
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| Authors(kana) | |
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| Organization | *東京大学医学部放射線医学教室, **附属病院第一外科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1463-1473 |
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| Year/Month | 1991/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」肝腫瘍の化学治療に際して経動脈注入肝シンチグラフィを施行した11例と, 大腸癌の肝転移の予防的化学治療に際して経門脈注入肝シンチグラフィを施行した6例について検討した. 撮像は, 肝動脈内または門脈内に留置されたカテーテルより, 99mTcスズコロイドまたは99mTcフチン酸111〜222 MBq (3〜6 mCi)を注入して行った. 99mTcフチン酸を経動脈注入した場合は, 肝初回通過時の取り込み効率が低く, 十分な情報が得られなかったが, 99mTcスズコロイドを用いた経動脈注入, 経門脈注入肝シンチグラフィ, および99mTcフチン酸を用いた経門脈注入肝シンチグラフィにより, 肝内RI分布の不均一性, 脾臓の描出, 腫瘍に相当する低集積域とその周囲の高集積といった所見が得られ, 経動脈注入, 経門脈注入化学療法の有効性を確認する上で有用な検査方法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-Sn colloid, 99mTc-phytate, Intra-arterial, Intraportal, Liver scintigraphy. |
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| English |
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| Title | Intra-arterial and Intraportal Infusion Liver Scintigraphy Using 99mTc-Labeled Colloid |
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| Subtitle | - Original Articles - |
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| Authors | Yusuke INOUE*, Tohru OHTAKE*, Toshimitsu MOMOSE*, Toshiaki WATANABE*, Noboru KOSAKA*, Jun-ichi NISHIKAWA*, Yasuhito SASAKI*, Toshio SAWADA**, Tetsuichiro MUTO** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **First Department of Surgery, Faculty Medicine, University of Tokyo |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1463-1473 |
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| Year/Month | 1991/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Intra-arterial infusion liver scintigraphy was performed in 11 patients with primary or metastatic liver tumor, and intraportal infusion liver scintigraphy was performed in 6 patients for prophylaxis of liver metastasis from colorectal cancer. 99mTc-Sn colloid or 99mTc-phytate was administered through the catheter of which tip was placed in the portal vein or the hepatic artery, and then liver image was obtained. When 99mTc-phytate was infused intra-arterially, significant amount of the infused tracer passed through the liver and we could not get sufficient information to assess the distribution of drug administered through the catheter. On the other hand, intraportal infusion liver scintigraphy using 99mTc-Sn colloid or 99mTc-phytate and intra-arterial infusion liver scintigraphy using 99mTc-Sn colloid revealed heterogenity of liver uptake, tracer uptake in spleen, low uptake area corresponding to the liver tumor and high uptake area around it. The findings will be clinically useful, and these methods are thought to be helpful to confirm the satisfactory drug distribution. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-Sn colloid, 99mTc-phytate, Intra-arterial, Intraportal, Liver scintigraphy. |
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