| Japanese |
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| Title | 心筋viabilityの定量的評価法 (viability map) の開発とその臨床応用 |
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| Subtitle | ≪原著≫ |
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| Authors | 小川洋二*, 西村恒彦*, 植原敏勇*, 片渕哲朗*, 下永田剛*, 林田孝平*, 汲田伸一郎* |
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| Organization | *国立循環器病センター放射線診療部 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1429-1437 |
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| Year/Month | 1991/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」運動負荷Tl心筋シンチグラフィによる心筋viabilityの定量的評価法を開発し, 前下行枝1枝障害71例を対象に臨床応用を行った. 心筋SPECT展開図表示を用い, 晩期像から早期像をsubtractionすることによって再分布した領域を画像化した(viability map). また, viable areaの拡がりをExtent score, viabilityの程度をViability scoreとして定量化した. 心筋梗塞ではExtent scoreは小さいが, Viability scoreの分布は広く, Extent scoreの大きい狭心症とは異なった分布をとった. 心筋梗塞例において, 早期像における血流欠損scoreからの変化として百分率表示した%scoreを, 梗塞部再分布の視覚的判定と対比すると, %Viability score>36, または, %Extent score>16の診断基準にて, 視覚的判定とよく一致した. この基準による定量的評価は, 臨床経過も反映していた. 本評価法は心筋viabilityの拡がり, 程度を定量化できる点で画期的だが, 再静注法やPET検査等との対比, および多枝病変における有用性についてはさらなる検討を要する. |
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| Practice | 臨床医学：一般 |
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| Keywords | Tl-201 myocardial SPECT, Quantitative evaluation, Myocardial viability, Unfolded map, Viability map. |
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| English |
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| Title | Quantitative Evaluation of Myocardial Viability using Tl-201 Myocardial SPECT |
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| Subtitle | - Original Articles - |
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| Authors | Yoji OGAWA, Tsunehiko NISHIMURA, Toshiisa UEHARA, Tetsuro KATAFUCHI, Tsuyoshi SHIMONAGATA, Kohei HAYASHIDA, Shin-ichiro KUMITA |
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| Authors(kana) | |
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| Organization | Department of Radiology and Nuclear Medicine, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 12 |
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| Page | 1429-1437 |
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| Year/Month | 1991/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In order to evaluate myocardial viability, we developed a new method for quantification of redistributed area in Tl-201 myocardial SPECT, and it was applied to 71 patients with LAD lesion. Initial image was subtracted from delayed image, and redistributed area was displayed as an unfolded map (viability map). Extent and viability score, which correspond to extent and degree of the viable area, was also calculated. In the cases with prior myocardial infarction, viability score was widely distributed and extent score was smaller, while the cases with angina pectoris had larger extent score. Visual assessment of redistribution to the infarcted area was compared with % score, which was calculated as ratio to initial defect score. When the criteria of viability was defined as % viability score >36 or % extent score >16, quantitative evaluation agreed with visual assessment, and corresponded to clinical course. This method was considered to be effective for evaluation of extent and degree of myocardial viability, but further evaluation need to be done in comparison with reinjection, PET study, and so on, and usefulness in multi-vessel disease. |
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| Practice | Clinical medicine |
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| Keywords | Tl-201 myocardial SPECT, Quantitative evaluation, Myocardial viability, Unfolded map, Viability map. |
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