| Japanese |
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| Title | 拡張型心筋症の予後 - 右心機能との関連 - |
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| Subtitle | 原著 |
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| Authors | 大野朗*, 西村恒彦*, 植原敏勇*, 下永田剛*, 汲田伸一郎*, 小川洋二*, 永田正毅**, 宮武邦夫** |
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| Organization | *国立循環器病センター放射線診療部, **心臓内科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 9 |
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| Page | 1075-1079 |
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| Year/Month | 1991/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」拡張型心筋症(以下DCM)の予後と, 心プールシンチグラフィ法により得られた右心機能との関連について検討した. 対象はDCM連続57症例(男性41人, 女性16人)で平均年齢は48歳(3-68歳), 左室駆出分画(LVEF)は29±11%(以下, 平均±標準偏差), 心不全症状発症よりの平均年数4年(0-33年)であった. 心プールシンチグラフィ検査施行日を起点として平均3.8±2年の予後追跡にて1年で6例, 3年で14例が死亡した. 3年時において重回帰分析にて臨床因子と予後との関連性を評価したところ, 内服内容, NYHA分類の2点で予後との有意な関連がみられた, Kaplan-Meier法による生存率評価では, 平均肺動脈圧(以下mPA)においては18mmHgを境界とする2群で3年予後に, また右室駆出分画(RVEF)においては45%を境界とする2群で7年予後にそれぞれ危険率6%で有意差を生じた. RVEFは, 非観血的なDCMの予後予測因子として役立つと考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | DCM, RVEF, Prognosis. |
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| English |
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| Title | Prognostic Significance of Radionuclide-Assessed Right Ventricular Function in Dilated Cardiomyopathy |
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| Subtitle | Original Articles |
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| Authors | Akira OHNO*, Tsunehiko NISHIMURA*, Toshiisa UEHARA*, Tsuyoshi SHIMONAGATA*, Shinichiro KUMITA*, Youji OGAWA*, Seiki NAGATA**, Kunio MIYATAKE** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Cardiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 9 |
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| Page | 1075-1079 |
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| Year/Month | 1991/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To assess the prognostic significance of right ventricular function in dilated cardiomyopathy (DCM), we studied consecutive 57 DCM patients. There were 41 men and 16 women, whose mean age was 48 ys. (range 3-68 ys.). The mean LVEF in all patients was 29 +- 11 %, and the mean interval from the onset of symptom of cardiac failure (CHF history) was 4 ys. (range 0-33 ys.). With follow-up of 3.8 ys., five patients had died until the first year, and 14 had died until the third year. By using multivariate regression analysis, there were no prognostic significance in clinical parameters such as age, CHF history, sex, atrial fibrillation, except for NYHA class, and medication at the third year. In survival curves according to Kaplan-Meier method, RVEF and mean PA had predictive value (p<0.05), while LVEF did not. The patients with RVEF<45% had poor survival rate compared to those with RVEF >= 45%. The patients with RVEF<45% showed lower LVEF and LVESVI. RVEF may offer prognostic predictive value through the effect of not only mean PA but also left ventricular parameter. In conclusion, radionuclide assessment of right ventricular function should be valuable for the prognostic evalua-tion of DCM patients. |
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| Practice | Clinical medicine |
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| Keywords | DCM, RVEF, Prognosis. |
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