| Japanese |
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| Title | Q波梗塞と非Q波梗塞における梗塞領域の心筋血流量, 心筋FDG集積の定量的検討 |
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| Subtitle | 原著 |
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| Authors | 高橋晶*, 飯田秀博**, 菅野巖**, 小野幸彦*, 田村芳一*, 宍戸文男**, 犬上篤**, 村上松太郎**, 三浦修一**, 上村和夫**, 佐藤匡也***, 阿部芳久***, 門脇謙***, 熊谷正之*** |
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| Authors(kana) | |
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| Organization | *秋田県立脳血管研究センター内科, **放射線科, ***秋田県成人病医療センター循環器科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 9 |
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| Page | 1029-1034 |
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| Year/Month | 1991/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」PETによって心筋梗塞症例における局所心筋血流量(以下MBF)とFDGの心筋集積(以下MFU)について定量的に検討した. 対象は, Q波梗塞例7例と非Q波梗塞例5例である. MBFは15O標識水のダイナミックPETにより, MFUはフルオロデオキシグルコース(以下FDG)のダイナミックPETによりそれぞれ測定した. これらは, いずれも組織含有率で補正し, 部分容積効果の影響を除いた. 非Q波梗塞の部位でのMBF(0.74±0.29ml/min/g)は, Q波梗塞の部位でのMBF(0.36±0.14ml/min/g)より有意に高値であった(p<0.005). また, 非Q波梗塞でのMFU(0.061±0.028)は, Q波梗塞でのMFU(0.038±0.017)より有意に高値を示した. 今回の測定から, 今後症例の積み重ねによりQ波出現の閾値を求めることが可能になると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Myocardial blood flow, Fluoro-deoxyglucose, Myocardial infarction, Q-wave, PET. |
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| English |
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| Title | The Quantitative Evaluation of Myocardial Blood Flow and Myocardial FDG Uptake in the Infarcted Lesions with Q-Wave and without Q-Wave Determined by O-15 Water, FDG and PET |
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| Subtitle | Original Articles |
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| Authors | Akira TAKAHASHI*, Hidehiro IIDA*, Iwao KANNO*, Yukihiko ONO*, Yoshikazu TAMURA*, Fumio SHISHIDO*, Atsushi INUGAMI*, Matsutaro MURAKAMI*, Shuuichi MIURA*, Kazuo UEMURA*, Tadaya SATO**, Yoshihisa ABE**, Ken KADOWAKI**, Tadayuki KUMAGAI** |
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| Authors(kana) | |
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| Organization | *Research Institute for Brain & Blood Vessels, **Akita Medical Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 9 |
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| Page | 1029-1034 |
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| Year/Month | 1991/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Cardiac PET elicits an accurate relationship between myocardial blood flow (MBF) and tissue viability, which is evaluated by myocardial FDG uptake (MFU). To differentiate reversible tissue from necrotic tissue after the ischemic event, we measured absolute MBF and MFU in patients with myocardial infarction. The MBF obtained by O-15 water and dynamic PET was accurately corrected by employing a tissue fraction (α) for the partial volume effect, including wall-motion effect. MFU was also corrected by using the tissue fraction. The subjects consisted of 5 patients with non-Q-wave infarction and 7 patients with Q-wave infarction. The regions of interest were selected from the infarcted area, each corresponding to regions with Q-wave or non-Q-wave. The MBFs in regions with Q wave (0.36 +- 0.14 ml/min/g) were lower than those without Q wave (0.74 +- 0.29 ml/ min/g)(p<0.005). MFUs in regions without Q-wave (0.061 +- 0.028) were higher than those with Q-wave (0.038 +- 0.017) (p<0.05). The highest threshold of MBF in regions where Q-wave was detected was 0.55 ml/min/g. It is concluded that we will able to find the threshold of electro-physiological dysfunction in the infarcted region with this method. |
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| Practice | Clinical medicine |
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| Keywords | Myocardial blood flow, Fluoro-deoxyglucose, Myocardial infarction, Q-wave, PET. |
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