| Japanese |
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| Title | 99mTc-DTPA-HSAによる腸骨骨盤部リンパシンチグラフィの検討 |
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| Subtitle | 研究速報 |
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| Authors | 末松徹*, 吉田祥二*, 小河幹治*, 藤原博文*, 元原智文*, 小泉正*, 三枝智恵子*, 池田幸央*, 上田英二*, 広田佐栄子*, 大林加代子*, 石田輝子*, 高田佳木* |
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| Organization | *兵庫県立成人病センター放射線科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 7 |
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| Page | 785-789 |
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| Year/Month | 1991/7 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」悪性腫瘍の腸骨骨盤部リンパ節転移例に対し, 99mTc-DTPA-HSAによるリンパシンチグラフィを行い, その有用性について検討した. 対象は正常5例, 癌の転移9例および悪性リンパ腫1例である. 両第1・2趾間に計185MBq (5mCi) / 0.25mlの99m-Tc-DTPA-HSAを皮内注射した. 約30秒間マッサージと約2分の歩行の後, 対向型全身用ガンマカメラを用いて投与後5〜15分の全身像を撮像した. 正常全例でバックグラウンドの放射能がほとんどない, 下肢から胸管末端までのリンパ系の像が得られた. 癌転移例の異常所見とその出現率はリンパ本幹の途絶 (55.9%), 胸管の描出の欠如 (44.4%), リンパ節への集積低下 (88.9%), 側副路の形成 (44.4%) および皮膚逆流 (22.2%) であった. 悪性リンパ腫ではさらに腫大リンパ節への集積を認めた. 99mTc-DTPA-HSAリンパ節シンチグラフィはリンパ系の異常を短時間かつ明瞭に診断できる検査法であると考える. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-DTPA-HSA, Lymphoscintigraphy, Metastasis, Neoplasm. |
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| English |
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| Title | Lymphoscintigraphy with 99mTc-DTPA-HSA : Detection of Metastases to Iliopelvic Lymph Nodes |
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| Authors | Toru SUEMATSU, Shoji YOSHIDA, Kanji OGAWA, Hirofumi FUJIWARA, Tomofumi MOTOHARA, Tadashi KOIZUMI, Chieko MIEDA, Yukio IKEDA, Eiji UEDA, Saeko HIROTA, Kayoko OHBAYASHI, Teruko ISHIDA, Yoshiki TAKADA |
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| Authors(kana) | |
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| Organization | Department of Radiology, Hyogo Medical Center for Adults |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 7 |
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| Page | 785-789 |
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| Year/Month | 1991/7 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The purpose of this study was to evaluate 99mTc-DTPA-HSA as an iliopelvic lymphoscintigraphic agent in 5 normal volunteers and 10 patients with metastases of malignant tumors (cancer, 9 ; and malignant lymphoma, 1) to the iliopelvic lymph nodes. The subjects underwent intradermal injection of 185 MBq of 99mTc-DTPA-HSA into digital web spaces of the feet. Massage was applied at the injection sites for 30 sec ; the subjects then walked around for 2 min. Whole-body scintigrams were obtained 5 min after injection. The whole-body scanning speed was 20 cm/min. The tracer transport was prompt. Within 15 min after injection, the tracer reached the termination of the thoracic duct in all normal volunteers. Normal whole-body images of excellent quality delineated the lymph nodes and channels almost without background radioactivity. The images of 9 patients with metastases of cancer showed clearly the following abnormal patterns : a) obstruction of lymphatic system (5 / 9, 55.6%) ; b) absence of visualization of the thoracic duct (44.4%) ; c) decreased uptake in lymph nodes (88.9%) ; d) visualization of collateral circulation (44.4%) ; e) tracer extravasation into more proximal soft tissue (22.2%). The image in the patient with malignant lymphoma showed increased uptake in the enlarged lymph nodes in addition to the all abnormal findings mentioned above. We concluded that 99mTc-DTPA-HSA is an excellent radiopharmaceutical for iliopelvic lymphoscintigraphy. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-DTPA-HSA, Lymphoscintigraphy, Metastasis, Neoplasm. |
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