| Japanese |
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| Title | Tl-201心筋シンチグラフィにおける心筋摂取率の検討 - 全身分布像を用いて - |
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| Subtitle | 原著 |
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| Authors | 足立至 |
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| Organization | 大阪医科大学放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 7 |
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| Page | 729-735 |
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| Year/Month | 1991/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Tl-201心筋シンチグラフィ上, 欠損, 肥大等を有さない症例に全身分布像を撮像し心筋摂取率, 肺野, 縦隔に対する比率, 各臓器の洗い出し率の3項目について検討した. 対象は運動負荷17例, dipyridamoleによる薬物負荷15例, 安静法20例の合計52例である. 心筋摂取率は運動負荷早期像6.3±0.8%, 薬物負荷早期像9.1±1.4%, 安静法7.1±1.2%であり薬物負荷は運動負荷 (p < 0.001), 安静法 (p < 0.01) に比較して有意に高かった. 薬物負荷は肺野に対する心筋の摂取比も2.2±0.17倍, 縦隔に対しても2.5±0.29倍と, 運動負荷に比較して有意に高かった (p < 0.05). 骨格筋の洗い出し率は薬物負荷と安静法の数値とは類似していた. 以上より薬物負荷心筋シンチグラフィは種々の心疾患, 運動機能の低下した症例に使用可能といった長所に加えて, 本検査法は他の方法に比較しより心筋摂取率が高く, 明瞭な心筋像が得られ, かつ骨格筋の動態については安静法と類似した方法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201, Myocardial scintigraphy, Whole body imaging, Dipyridamole. |
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| English |
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| Title | Evaluation of Myocardial Uptake of Thallium-201 in Whole Body Scintigraphy |
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| Subtitle | |
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| Authors | Itaru ADACHI |
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| Organization | Department of Radiology, Osaka Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 7 |
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| Page | 729-735 |
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| Year/Month | 1991/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Whole body scintigraphy (WBS) was performed to assess the myocardial uptake in the dipyridamole (DP), exercise loading (EX) and thallium-201 (Tl-201) myocardial scintigraphy. DP-WBS was studied in 15 patients (pts), EX-WBS was studied in 17 pts and resting (RE) - WBS was studied in 20 pts. All pts had some kinds of heart disease clinically, but their myocardial scintigraphy showed no abnormal findings. DP-WBS and EX-WBS were performed both immediately (early image DP-E, EX-E) and 3 hours later (delayed image EX-D, DP-D) after injection of Tl-201. RE-WBS were performed immediately (early image REST) after injection of Tl-201 only. The percent myocardial uptake, background ratio of the myocardium and washout ratio of some organs were calculated from the ROIs (region of interest) over the whole body, heart, lung, mediastinum, abdomen and thighs. The myocardial uptake of DP-E was 9.1 +- 1.4%, myocardial uptake of EX-E was 6.3 +- 0.8% and myocardial uptake of REST was 7.1 +- 1.2%. The thighs uptake of DP-E was 10.4 +- 1.1%, thighs uptake of EX-E was 25.3 +- 2.6% and thighs uptake of EX-E was 25.3 +- 2.6% and thighs uptake of REST was 10.1 +- 1.5%. The percent myocardial uptake of DP-E was not only higher than that of EX-E (p < 0.001) but also higher than that of REST (p < 0.01). Thus, we conclude that DP scintigraphy showed clearer myocardial image than EX scintigraphy. From the similarity of thighs uptake between DP scintigraphy and RE scintigraphy, we considered that Tl-201 kinetics of the skeletal muscle in DP scintigraphy was similar to that in RE scintigraphy. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201, Myocardial scintigraphy, Whole body imaging, Dipyridamole. |
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