| Japanese |
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| Title | 平衡時心プールシンチグラフィによる経皮経静脈的僧帽弁裂開術の効果の評価 - 心房細動を合併する僧帽弁狭窄症におけるリストモード法による検討 - |
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| Subtitle | 原著 |
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| Authors | 中村誠志*, 岩坂壽二*, 木村穣*, 大久保直彦*, 松浦隆*, 稲田満夫*, 白石友邦** |
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| Authors(kana) | |
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| Organization | *関西医科大学第二内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 7 |
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| Page | 711-717 |
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| Year/Month | 1991/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」心房細動を有する僧帽弁狭窄症8例において, 平衡時心プールシンチグラフィを用い, 左室拡張早期充満動態の変化を検討し, 経皮経静脈的僧帽弁裂開術 (PTMC) の効果を判定することを目的とした. データ収集はリストモード法を用い, 約1,000心拍を収集, その後作成した心拍分布より最も頻度の高い心拍の前後5%の心拍のみをレフームモードに再編集して処理を行い, 得られた左室容量曲線より左室駆出分画, Peak filling rate (PFR) を算出した. PTMC前後で投与薬剤量の変化はなかった. 僧帽弁口面積は, 1.3±0.5cm2より2.0±0.6cm2 (p < 0.01), 左房左室圧較差は, 12.4±5.9mmHgより4.9±3.7mmHg (p < 0,01), 臨床症状は全例で改善した. 左室駆出分画は, 43±9%より48±13%と不変であったが, PFRは, 1.5±0.3 EDV / secより2.0±0.4 EDV / sec (p < 0.01) と有意に改善した. 以上より, 本法で得られたPFRは非侵襲的に, PTMC後の左室拡張早期充満動態を評価し得る指標であると考えた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Percutaneous transvenous mitral commissurotomy, Equilibrium radionuclide angiocardiography, Peak filling rate, Atrial fibrillation, List mode method. |
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| English |
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| Title | Radionuclide Assessment of Left Ventricular Diastolic Function in Patients with Mitral Stenosis Before and After Percutaneous Transvenous Mitral Commissurotomy ; Use of List Mode Method in Patients with Atrial Fibrillation |
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| Subtitle | Original Articles |
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| Authors | Seishi NAKAMURA*, Toshiji IWASAKA*, Yutaka KIMURA*, Naohiko OHKUBO*, Takashi MATSUURA*, Mitsuo INADA*, Tomokuni SHIRAISHI** |
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| Authors(kana) | |
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| Organization | *Second Department of Internal Medicine, **Department of Radiology, Kansai Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 7 |
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| Page | 711-717 |
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| Year/Month | 1991/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To evaluate the effect of percutaneous transvenous mitral commissurotomy (PTMC), equilibrium radionuclide angiocardiography was performed in eight patients with mitral stenosis who had atrial fibrillation. Accurate cardiac function in patients with atrial fibrillation is difficult to assess, since the wide fluctation of cardiac cycle makes the ventricular hemodynamics variable. A new processing algorhythm was devised to make multiple gated images discriminated from a heart rate distribution histogram. We obtained about 1,000 beats data by list mode acquisition, and processed a heart rate distribution histogram. The data in the area +- 5% of the most frequent heart rate were converted into frame mode and a representative time activity curve was derived. Mitral valve area caliculated by echocardiography increased from 1.3 +- 0.5 to 2.0 +- 0.6 (cm2) significantly (p < 0.01). The mean transmitral pressure gradient measured by catheterization decreased from 12.4 +- 5.9 to 4.9 +- 3.7 (mmHg) significantly (p < 0.01) and the clinical symptoms improved in all patients. The change in left ventricular ejection fraction from 43 +- 9 to 48 +- 13 (%) was not statistically significant, but peak filling rate (PFR) derived from the time activity curve increased from 1.5 +- 0.3 to 2.0 +- 0.4 (EDV / sec) significantly (p < 0.01). Thus PFR is a noninvasive parameter that can evaluate the effect of PTMC. |
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| Practice | Clinical medicine |
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| Keywords | Percutaneous transvenous mitral commissurotomy, Equilibrium radionuclide angiocardiography, Peak filling rate, Atrial fibrillation, List mode method. |
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