| Japanese |
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| Title | 99mTc-ECDを用いた脳血管障害における脳血流シンチグラフィ - 123I-IMP SPECTとの比較 - |
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| Subtitle | 原著 |
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| Authors | 小川洋二*, 西村恒彦*, 林田孝平*, 与小田一郎*, 今北哲*, 汲田伸一郎*, 植原敏勇*, 下永田剛*, 岡尚嗣*, 中村雅一**, 長谷川泰弘** |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部, **内科脳血管部門 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 6 |
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| Page | 599-607 |
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| Year/Month | 1991/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」脳血管障害19例を対象として99mTc-ECD SPECTを施行し, 全身および脳内分布の検討を行った. また, 病変の部位, 拡がり, 描出能について123I-IMP SPECTと比較した. 99mTc-ECDの脳への摂取率は投与後10分で5.5%に達し, 90分でも5.3%が保持された. SPECT像にて脳内分布は経時的に変化し, 特に視床にて低い洗い出し率を示した. 病変部と対側正常部のカウント比 (D / N比) は経時的に変化せず, 123I-IMP SPECTと同等の値を示した. 99mTc-ECD SPECTは基底核部の病変の描出に優れ, 123I-IMP SPECTよりも高い基底核 / 白質比を示した. また, 高分解能型コリメータの使用により空間分解能の高い画像が得られ, 99mTc標識の特性が生かされていた. 一方, 軽度の血流低下部や梗塞周辺部の描出では123I-IMP SPECTに劣る傾向が認められた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-ECD, 123I-IMP, Cerebrovascular disease. |
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| English |
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| Title | Cerebral Perfusion Scintigraphy in Patients with Cerebrovascular Disease by Using 99mTc-ECD : Comparative Study with 123I-IMP SPECT |
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| Subtitle | Original Articles |
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| Authors | Yoji OGAWA*, Tsunehiko NISHIMURA*, Kohei HAYASHIDA*, Ichiro YOKOTA*, Satoshi IMAKITA*, Shin-ichiro KUMITA*, Toshiisa UEHARA*, Tsuyoshi SHIMONAGATA*, Hisashi OKA*, Masakazu NAKAMURA**, Yasuhiro HASEGAWA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, **Department of Medicine, Cerebrovascular Division, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 6 |
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| Page | 599-607 |
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| Year/Month | 1991/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 99mTc-ECD SPECT was performed in 19 patients with cerebrovascular disease, and location, extent, and severity of the lesions on 99mTc-ECD SPECT were compared with those on 123I-IMP SPECT. The initial brain uptake was 5.5 +- 0.7% of the injected dose at 10 minites after injection, 5.3 +- 1.3% at 90 minites, and clearance from the brain is slow. The distribution in the brain was changed, especially washout from the thalamus was slower than that from other regions. The count ratio of perfusion defect to normal area (D / N) on 99mTc-ECD SPECT was unchanged over the time, and had no significant differences from that on 123I-IMP SPECT. 99mTc-ECD SPECT was superior in detection of the lesion in the basal ganglia, and showed the images with superior spatial resolution due to physical characteristics of 99mTc. However, mild ischemic lesion and periinfarct area was not clearly visualized, while 123I-IMP SPECT could demonstrate these lesions with better contrast. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-ECD, 123I-IMP, Cerebrovascular disease. |
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