| Japanese |
|---|
| Title | 99mTc-MIBIを用いた心機能評価 - GATED PLANAR IMAGEによる検討 - |
|---|
| Subtitle | 原著 |
|---|
| Authors | 汲田伸一郎*, 西村恒彦*, 植原敏勇*, 下永田剛* |
|---|
| Authors(kana) | |
|---|
| Organization | *国立循環器病センター放射線診療部 |
|---|
| Journal | 核医学 |
|---|
| Volume | 28 |
|---|
| Number | 6 |
|---|
| Page | 591-597 |
|---|
| Year/Month | 1991/6 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」新しい心筋血流トレーサ99mTc-MIBIを用いた心機能評価につき検討を行った. 健常volunteer 5例, 各種心疾患症例39例に99mTc-MIBI 555〜740MBq (15〜20mCi) を安静時に投与し, 3時間後に心拍同期プラナー心筋シンチグラフィを施行した. 心筋左前斜位 (ED, ES) イメージにcircumferential profile analysisを行い, 左室収縮にともなう心筋count densityの上昇 (%count increase ; CI) を測定し, これを用いた心機能評価法を開発した. Global %CIは左室カテーテル造影検査 (LVG) ならびに心拍同期心プールシンチグラフィより算出したLVEF (%) と良好な相関を示した (r = 0.70 ; n = 29, r = 0.75 ; n = 24). また局所 (Regional) %CIはLVGにおける視覚的壁運動評価をよく反映し, 壁運動低下部では有意に低値を示した. 本法は簡便かつ臨床的に心筋灌流と心機能が同時に推定できる有用な検査法であると思われる. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | 99mTc-MIBI, Gated planar imaging, Circumferential profile analysis, %count increase. |
|---|
| English |
|---|
| Title | Evaluation of Left Ventricular Function Using Gated Planar Myocardial Imaging with Tc-99m-MIBI |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Shin-ichiro KUMITA, Tsunehiko NISHIMURA, Toshiisa UEHARA, Takeshi SHIMONAGATA |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Radiology, National Cardiovascular Center |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 28 |
|---|
| Number | 6 |
|---|
| Page | 591-597 |
|---|
| Year/Month | 1991/6 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] A quantitative index of left ventricular wall motion obtained from ECG-gated planar myocardial images has been developed. Five normal controls and 39 patients with heart disease received an injection of Tc-99m-MIBI (550 - 740MBq) at rest, and ECG-gated planar scintigraphy (LAO view) was performed 3 h later. Mean End-diastolic (ED) and end-systolic (ES) myocardial activities were measured using circumferential profile analysis and %count increase (CI) was determined according to the following formula ; (ES count-ED count) / (ED count)×100. The global %CI was compared with the EF obtained from contrast ventriculography (LVG ; n = 29) and radionuclide ventriculography using Tc-99m-labelled RBC (RNV ; n =24). The regional %CI was compared with left ventricular wall motion assessed by LVG. The global %CI was correlated well with EF by LVG (r = 0.70) and EF by RNV (r = 0.75). The regional %CI significantly decreased in accordance with wall motion on LVG worsened at impaired region. In conclusion, gated perfusion imaging with Tc-99m-MIBI provides useful information on ventricular function in addition to myocardial perfusion. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | 99mTc-MIBI, Gated planar imaging, Circumferential profile analysis, %count increase. |
|---|