| Japanese |
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| Title | 心筋梗塞急性期における障害心筋salvage推定 - Tc-99m PYP, Tl-201 Dual SPECTと慢性期運動負荷再静注Tl Scintigraphyからみた心筋Viabilityとの対比検討 - |
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| Subtitle | ≪原著≫ |
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| Authors | 松尾仁司*, 渡辺佐知郎*, 荒井政澄*, 琴尾泰典*, 大橋宏重*, 小田寛*, 上野勝己*, 松原徹夫*, 大野道也*, 森省一郎*, 後藤明**, 近藤紀博**, 牧田一成**, 石黒源之*** |
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| Authors(kana) | |
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| Organization | *県立岐阜病院循環器科腎臓科, **中央放射線部, ***平野総合病院内科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 5 |
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| Page | 477-485 |
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| Year/Month | 1991/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞部Viabilityの判定が急性期に可能かどうかを検討するため急性期Tl-201, Tc-99m PYP Dual SPECT所見と慢性期運動負荷再静注Tl所見とを比較した. 対象は初回心筋梗塞18例で, 障害心筋72区域中, 48区域(66.7%)が慢性期Tl所見上生存心筋と判定された. 急性期Tl所見ではTl取り込み正常領域100%, 軽度低下領域86%, 重度低下領域38%が慢性期生存心筋と判定された. PYP所見上は心内膜側限局型は, 有意に貫壁性に比較し慢性期生存心筋が多く(p<0.001), PYP局在の判定は予後予測の上で重要であると考えられた. またOverlap (+)領域では75%, Overlap (-)領域の33%が生存心筋と判定され有意にOverlap領域の予後が良好であった(p<0. 5). 梗塞部位慢性期Viabilityの評価には, Tl, PYP単独判定に比し, Dual SPECTによる判定の方がより良好な診断精度が得られた. 以上より心筋梗塞急性期Tl-PYP Dual SPECTは梗塞部位Viabilityの評価に有用である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Acute myocardial infarction, Tc-99m PYP, Tl-201 Dual SPECT, Exercise-Reinjection Tl SPECT, Myocardial viability. |
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| English |
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| Title | The Diagnostic Value of Tc-99m PYP, Tl-201 Dual Isotope SPECT to Predict the Viability of Damaged Myocardium in the Acute Phase of Myocardial Infarction - Comparison with Stress, Delayed, and Reinjected Tl-201 SPECT - |
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| Subtitle | - Original Articles - |
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| Authors | Hitoshi MATSUO*, Sachiro WATANABE*, Masazumi ARAI*, Yasunori KOTOO*, Hiroshige OOHASHI*, Hiroshi ODA*, Katsumi UENO*, Tetsuo MATSUBARA*, Michiya OHNO*, Shouitirou MORI*, Akira GOTOH**, Norihiro KONDO**, Kazunari MAKITA**, Motoyuki ISHIGURO*** |
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| Authors(kana) | |
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| Organization | *The Department of Cardiology and Nephrology, **The Department of Radiology, Gifu Prefectural Hospital, ***Hirano General Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 5 |
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| Page | 477-485 |
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| Year/Month | 1991/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To assess the diagnostic value of Tc-99m PYP, Tl-201 dual isotope SPECT for the evalustion of myocardial viability, segmental comparison between dual isotope SPECT and exercise, delayed, and reinjected Tl study were performed with 18 AMI patients. Among 72 damaged myocardial segments, 48 segments (67%) were judged as viable by chronic phase Tl studies. The segments with severely reduced Tl uptake by dual SPECT showed significantly lower prevalence of viable myocardium than the segments with reduced and normal Tl uptake (p<0.001). The segments with PYP accumulation localized to the subendocardium represented the favorable outcome compared with the transmural accumulation (p<0.001). And overlap segments show better prognosis than the segments without overlap (p<0.05). Most inportantly, we can get better predictive accurancy of myocardial scar by dual isotpe SPECT than the judgement by Tl or PYP SPECT Alone (83.3% vs 77.8%, 68.1%). Thus, we conclude that Tc-99m PYP, Tl-201 dual isotope SPECT is useful to assess the severity of myocardial damage in the acute phase of myocardial infarction. |
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| Practice | Clinical medicine |
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| Keywords | Acute myocardial infarction, Tc-99m PYP, Tl-201 Dual SPECT, Exercise-Reinjection Tl SPECT, Myocardial viability. |
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