Japanese
Title心筋梗塞症例におけるsilent myocardial ischemiaと予後との関連 - 運動負荷心筋スキャンを用いて -
Subtitle≪原著≫
Authors下永田剛*, 西村恒彦*, 植原敏勇*, 汲田伸一郎*, 小川洋二*, 大野朗*, 野々木宏**, 土師一夫**
Authors(kana)
Organization*国立循環器病センター放射線診療部, **内科
Journal核医学
Volume28
Number5
Page455-460
Year/Month1991/5
Article原著
Publisher日本核医学会
Abstract「要旨」梗塞症例の運動負荷心筋スキャン(EX-Tl)におけるsilent myocardial ischemia (SMI)の予後を検討する目的で, EX-Tlの施行された発症3か月以内の心筋梗塞149例にて2年間の予後を検討した. SMIの判定は, 胸痛を伴わない一過性欠損像とした. EX-Tlの結果にて, 149例は胸痛も一過性欠損像も出現しなかった50例(対照群), SMI群46例および胸痛の出現した53例(狭心症群)に分類された. 2年間の経過観察中, 狭心症群は, SMI群に比し有意にPTCA, CABGの施行頻度は高値を示したが, 他のcardiac eventの頻度に有意差はなかった. さらに, 2年間のcurdiac event-free曲線にて, SMI群と狭心症群のCEの出現率は対照群に比し有意に高値を示したが, SMI群と狭心症群間に有意差はなかった. 以上より, SMI群の予後は狭心症群と同様不良であり, SMI症例に対して厳重な経過観察が必要であると考えられた.
Practice臨床医学:一般
KeywordsSilent myocardial ischemia, Myocardial infarction, Stress thallium scan.
English
TitlePrognostic Significance of Scintigraphic Silent Myocardial Ischemia Detected by Stress Thallium Scan in Patients with Recent Myocardial Infarction
Subtitle- Original Articles -
AuthorsTsuyoshi SHIMONAGATA, Tsunehiko NISHIMURA, Toshiisa UEHARA, Shin-ichiro KUMITA, Youji OGAWA, Akira OHNO, Seiki HAMADA, Hiroshi NONOGI, Kazuo HAZE
Authors(kana)
OrganizationNational Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume28
Number5
Page455-460
Year/Month1991/5
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To evaluate the prognostic significance of scintigraphic silent myocardial ischemia (SMI) detected by stress thallium scan in patients with myocardial infarction (MI), we performed a retrospective investigation on cardiac events (CE) during a two-year follow-up period in 149 patients with MI within three months of onset (34 +- 19 days). SMI was defined as asymptomatic redistribution (RD) in the infarcted area. The patients were divided into three groups based on results of stress thallium scan as follows: 50 patients with neither chest pain nor RD (Group A), 46 patients with SMI (Group B) and 53 symptomatic patients (Group C). In comparison of the incidence of CE, which included cardiac death, recurrent MI, chronic heart failure, angina pectoris, PTCA, CABG and severe ventricular arrhythmia (lown grade >= 3) during two-year follow-up, Group C had significantly higher incidence of PTCA and CABG than Group B (p<0.01), but there was no significant difference of other CE between groups B and C except PTCA and CABG. In addition, Groups B and C had a significantly higher incidence of CE than Group A in cardiac event-free curves, but there was no significant difference for Groups B and C. We conclude that patients with SMI are associated with unfavorable prognosis as symptomatic patients and that these patients should undergo careful follow-up.
PracticeClinical medicine
KeywordsSilent myocardial ischemia, Myocardial infarction, Stress thallium scan.

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