| Japanese |
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| Title | 虚血性心疾患に対する, 低レベル運動負荷併用dipyridamole負荷心筋SPECTの診断能 - 同一症例での運動負荷心筋SPECT所見との比較 - |
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| Subtitle | ≪原著≫ |
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| Authors | 高尾祐治*, 村田啓*, 加藤健一**, 小野口昌久***, 大竹英二*, 趙圭一* |
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| Organization | *虎の門病院放射線科, **循環器センター内科, ***放射線部 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 4 |
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| Page | 361-370 |
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| Year/Month | 1991/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」低レベル運動負荷併用dipyridamole負荷心筋SPECT (Dp法)の虚血性心疾患の検出に対する有用性について, 同一症例(28例)に施行した通常の運動負荷心筋SPECT (Ex法)所見と比較検討した. Dp法の視覚判定による病変検出能はEx法と同等以上(accuracy 71% vs 67%)だった. また集積低下の程度と再分布の程度はともにDp法の方が強かった. Washout rate (WR)による定量解析では, 正常対照例(Dp法10, Ex法8)におけるDp法での平均WR値がEx法と同等の高値となり, 症例によるばらつきも小さかった. 狭心症14例でのWRによる病変検出能はDp法の方が有意に高値だった(accuracy 86% vs 64%; p<0.05). これらの結果は, Dp法がEx法より優れており, ルーティンの負荷法として有用である可能性を示した. 胸部症状とST低下所見の発現頻度はいずれも高率で, Dp法による欠損には, 相対的血流増加の差のみでなく, 心筋虚血の誘発も関与している可能性が高いと考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | dipyridamole, ischemic heart disease, thallium myocardial SPECT, low level exercise washout rate. |
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| English |
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| Title | Usefulness of Thallium-201 Myocardial SPECT Using Dipyridamole Infusion Combined with Low Level Exercise for the Detection of the Ischemic Heart Disease - Comparison with SPECT Images by Maximum Physical Exercise in the Same Patients |
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| Subtitle | - Original Articles - |
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| Authors | Yuji TAKAO*, Hajime MURATA*, Kenichi KATOH**, Masahisa ONOGUCHI*, Eiji OHTAKE*, Keiichi CHO* |
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| Authors(kana) | |
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| Organization | *Division of Nuclear Medicine, **Cardiovascular Center, Toranomon Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 4 |
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| Page | 361-370 |
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| Year/Month | 1991/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To evaluate the usefulness of thallium-201 myocardial SPECT using dipyridamole infusion combined with low level exercise (Dp-method) for the detection of the ischemic heart disease, we performed both Dp-method and maximum physical exercise SPECT (Ex-method) in the same 28 patients, and compared the results obtained by the two methods. In the visual evaluation, the detectability of each stenotic coronary territory by Dp-method tended to be higher than that by Ex-method (accuracy 71% vs 67%). The severity of the defect and the degree of the redistribution were higher by Dp-method than those by Ex-method. In the washout rate (WR) analysis in 14 angina pectoris patients, the detectability (accuracy) by Dp-method was significantly higher than that by Ex-method (86% vs 64%; p<0.05). In comparison of mean WR values in normal subjects (10 cases for Dp-method and other 8 cases for Ex-method), mean WR by Dp-method was as high as that by Ex-method and the deviation of WR value among subjects was very small. This was probably due to the effect of the low level exercise. These results suggested that Dp-method was more excellent than Ex-method in the evaluation of the ischemic heart disease, and was a useful method of the daily routine work. The incidence of chest symptom and the electrocardiographic ST-depression was as high by Dp-method as that by Ex-method. The filling defects in Dp-method were thought to be induced not only by the difference in the relative increase of the myocardial perfusion, but also by the myocardial ischemia. |
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| Practice | Clinical medicine |
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| Keywords | dipyridamole, ischemic heart disease, thallium myocardial SPECT, low level exercise washout rate. |
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