| Japanese |
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| Title | Technetium-99m methoxy isobutyl isonitrile (MIBI) による壁運動と心筋血流の同時評価 |
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| Subtitle | 研究速報 |
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| Authors | 竹石恭知*, 殿岡一郎*, 目黒光彦*, 千葉純哉*, 阿部真也*, 立木楷*, 駒谷昭夫**, 螻眞弘**, 高梨以美**, 高橋和栄*** |
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| Authors(kana) | |
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| Organization | *山形大学医学部第一内科, **放射線科, ***附属病院放射線部 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 3 |
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| Page | 297-300 |
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| Year/Month | 1991/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」冠動脈疾患を疑う12例を対象に, Technetium-99m methoxy isobutyl isonitrile (Tc-MIBI) を用いて, 安静時にfirst-pass法によるradionuclide angiographyに引き続き, 心筋SPECTイメージングを行った. 局所壁運動はnormal, hypokinesis, akinesis / dyskinesis (a / dyskinesis) の3段階に評価した. Tc-MIBIの心筋uptakeは, normal, reduced, absentと視覚的に判定した. 心筋のuptakeがnormal, reducedと判定されたsegmentのうち, 壁運動がa / dyskinesisを示したのはそれぞれ7%, 33%であった. しかし心筋のTc-MIBI uptakeがabsentのsegmentでは100%にa / dyskinesisを認めた. 心筋のTc-MIBI uptakeから壁運動異常の存在, 心筋viabilityを評価しえることが示唆された. 本法は壁運動と心筋血流の評価が同時に可能な有用な方法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Tc-99m methoxy isobutyl isonitrile, First-pass radionuclide angiography, Myocardial viability. |
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| English |
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| Title | Simultaneous Assessment of Wall Motion and Myocardial Perfusion by Technetium-99m Methoxy Isobutyl Isonitrile |
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| Authors | Yasuchika TAKEISHI*, Ichiro TONO-OKA*, Mitsuhiko MEGURO*, Jyunya CHIBA*, Shinya ABE*, Kai TSUIKI*, Akio KOMATANI**, Masahiro KERA**, Imi TAKANASHI**, Kazuei TAKAHASHI*** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, **Department of Radiology, ***Division of Radiology, Yamagata University Hospital, Yamagata University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 3 |
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| Page | 297-300 |
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| Year/Month | 1991/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The aim of this study was to assess whether or not myocardial uptake of Technetium-99m methoxy isobutyl isonitrile (Tc-MIBI) indicated myocardial viability. We performed simultaneous Tc-MIBI angiography and myocardial SPECT at rest on 12 patients with suspected coronary artery disease. Left ventricle was divided into 3 segments, and regional wall motion was graded as normal, hypokinesis and akinesis / dyskinesis. Myocardial uptake of Tc-MIBI was assessed as normal, reduced and absent in each segment. In segments with normal and reduced Tc-MIBI uptake, 7% (2 of 28) and 33% (2 of 6) showed wall motion abnormalities of akinesis / dyskinesis, respectively. However, all segments with absent Tc-MIBI uptake had asynergy of akinesis / dyskinesis (2 of 2, 100%). Myocardial Tc-MIBI uptake at rest indicated wall motion abnormalities and was considered to be useful for the evaluation of myocardial viability. First-pass radionuclide angiography followed by myocardial SPECT with Tc-MIBI demonstrated to be useful for the simultaneous assessment of the left ventricular wall motion and myocardial perfusion. |
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| Practice | Clinical medicine |
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| Keywords | Tc-99m methoxy isobutyl isonitrile, First-pass radionuclide angiography, Myocardial viability. |
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