| Japanese |
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| Title | 123I-IMPが高度に集積した肺腺癌の1例 |
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| Subtitle | 症例報告 |
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| Authors | 末松徹*, 吉田祥二*, 山本裕之**, 丸田力*, 小河幹治*, 河本英作***, 堀尾光三****, 楢林勇***** |
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| Authors(kana) | |
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| Organization | *兵庫県立成人病センター放射線科, **呼吸器科, ***兵庫県立柏原病院内科, ****神戸大学医学部第二病理学教室, *****大阪医科大学放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 3 |
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| Page | 293-296 |
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| Year/Month | 1991/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」123I-IMPが腫瘤に一致して高度に集積した原発性肺癌 (低分化腺癌) の症例を報告する. 右肺の異常陰影の精査を目的として来院した. 胸部X線像上, 右肺S10に長径60mmの腫瘤を認め, 気管支擦過細胞診にて腺癌と診断された. 123I-IMP静注24時間後にSPECT像を撮像したところ, 腫瘤に一致して高度の集積増加像を認めた. 患者は化学療法施行にもかかわらず, 腫瘍の胸膜進展に伴う全身状態の悪化の後, 十二指腸潰瘍からの出血が直接の原因となって死亡した. 剖検で123I-IMPの集積が腫瘤に一致していたことを確認した. 腫瘍部の病理組織像は低分化腺癌であった. 肺癌では腫瘤は低集積像を呈し, 腫瘤の周囲に高集積がみられるとされているが, 本症例のように稀に癌腫に一致して集積する症例があることに留意する必要がある. 「I. はじめに」123I-IMP肺シンチグラフィ後期像では, 無気肺や炎症巣などに一致して異常集積がみられることが知られている. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-IMP, Lung neoplasm, Radionuclide study. |
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| English |
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| Title | A Case of Increased 123I-IMP Uptake in Adenocarcinoma of the Lung |
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| Subtitle | |
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| Authors | Toru SUEMATSU*, Shoji YOSHIDA*, Hiroshi YAMAMOTO**, Tsutomu MARUTA*, Kanji OGAWA*, Eisaku KOMOTO***, Mitsuzo HORIO****, Isamu NARABAYASHI***** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Hyogo Medical Center for Adults, **Department of Respiratory Disease, Hyogo Medical Center for Adults, ***Department of Medicine, Hyogo Profectural Kaibara Hospital, ****The Second Department of Pathology, Kobe University School of Medicine, *****Department of Radiology, Osaka Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 3 |
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| Page | 293-296 |
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| Year/Month | 1991/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] It has been reported that delayed 123I-IMP lung scintigraphy shows a defect corresponding to the tumor with increased accumulation around the tumor, and that an increased accumulation is associated with atelectasis and inflammation. We presented a case of increased uptake of 123I-IMP in lung cancer. None of the other reported case of increased uptake in lung cancer, to our knowledge, occurred. A 55-year-old man had a 6 cm mass in the lower lobe of the right lung. Cytologic examination with a small curette diagnosed the case as an adenocarcinoma. The 123I-IMP scintigraphy was performed 24 hours after intravenous injection of 111 MBq of 123I-IMP. The 123I-IMP SPECT lung images showed an area of increased 123I-IMP concentration corresponding to the tumor mass. The patient's subsequent course was characterized by massive pleural effusion caused by extensive invasion to the pleura despite chemotheraphy. He died about 2 months after the 123I-IMP scintigraphy. The right lung removed at necropsy confirmed that the area of high 123I-IMP concentration corresponded to the mass, which proved a poorly differentiated adenocarcinoma. One should note that there is an unusual case with high 123I-IMP uptake in lung cancer. |
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| Practice | Clinical medicine |
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| Keywords | 123I-IMP, Lung neoplasm, Radionuclide study. |
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