| Japanese |
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| Title | 原発性肺高血圧症における肺血流シンチグラフィ |
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| Subtitle | ≪原著≫ |
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| Authors | 小川洋二*, 西村恒彦*, 汲田伸一郎*, 林田孝平*, 植原敏勇*, 下永田剛*, 大野朗* |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 2 |
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| Page | 177-183 |
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| Year/Month | 1991/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」原発性肺高血圧症15例を, 肺血流シンチグラフィにて不均一なRI分布(mottled pattern)を示す8例と, mottled patternを示さない7例の2群に分類し, 両群間で心・肺機能に関する各種検査成績, および予後を比較した. mottled patternを示す群では, 示さない群に比し高い平均肺動脈圧を呈し, 高度の肺血管床の障害が示唆された. 右室駆出分画はほぼ全例で著明に低下しており, 両群間で差はなかった. 動脈血酸素分圧(PaO2), 肺胞動脈血酸素分圧較差(A-aDo2)についても差は認めなかった. 肺血流シンチグラフィ施行時を起点とした2年生存率はmottled patternを示す群が0%, 示さない群が57%で, 両群の生存率曲線には有意な差を認めた. したがって, 肺血流シンチグラフィは, 原発性肺高血圧症において, 診断のみならず予後の評価にも有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | primary pulmonary hypertension, perfusion lung scan, prognosis. |
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| English |
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| Title | Perfusion Lung Scintigraphy in Primary Pulmonary Hypertension |
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| Subtitle | - Original Articles - |
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| Authors | Yoji OGAWA, Tsunehiko NISHIMURA, Shin-ichirou KUMITA, Kohei HAYASHIDA, Toshiisa UEHARA, Tsuyoshi SHIMONAGATA, Akira OHNO |
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| Authors(kana) | |
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| Organization | Department of Diagnostic Radiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 2 |
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| Page | 177-183 |
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| Year/Month | 1991/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Fifteen cases with primary pulmonary hypertension (PPH) were classified into two groups by using the perfusion lung scan pattern. Eight cases had multiple, small, ill-defined defects (mottled pattern), and remaining seven cases had no mottled pattern. These two groups were compared with mean pulmonary arterial pressure (mean PAP), right ventricular ejection fraction (RVEF), blood gas at room air (PaO2), and alveolar-arterial O2 difference (A-aDo2). The cases with mottled pattern showed a significant increase in mean PAP. There were no significant differences in RVEF, PaO2, and A-aDo2, between the groups. The survival rate of the patients with mottled pattern was significantly lower than that without mottled pattern (p<0.05). We concluded that perfusion lung scan is very useful for evaluation of the prognosis in primary pulmonary hypertension. |
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| Practice | Clinical medicine |
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| Keywords | primary pulmonary hypertension, perfusion lung scan, prognosis. |
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