Japanese
Title心電図同期心プールシンチ断層法による左心機能の評価
Subtitle原著
Authors成田充啓*, 栗原正*, 村野謙一*, 宇佐美暢久*, 本田稔**
Authors(kana)
Organization*住友病院内科, **住友病院アイソトープ検査部
Journal核医学
Volume28
Number1
Page51-61
Year/Month1991/1
Article原著
Publisher日本核医学会
Abstract「要旨」99mTcによる心電図同期心プールシンチ断層法 (SPECT) の左室容積, 左室駆出率 (EF) の計測や左室壁運動評価における有用性を冠動脈疾患18例で検討した. 左室容積は左室を構成する総voxel数を求めこれをもとに計測した. 心プールファントム実験より左室辺縁を抽出するカットオフレベルはバックグラウンドの程度, 左室の容積そのものによって影響されることが示されたため, 各バックグラウンド別に容積 - カットレベル曲線を作成, これをもとに症例ごとに, また拡張終期, 収縮終期で異なる左室辺縁抽出の至適カットオフレベルを求めこれより左室拡張終期および収縮終期容積 (EDV, ESV) を計測した. SPECTで求めたEDV, ESV, EFと左室造影 (LVG) で求めたこれら指標の間にはおのおのr = 0.89, 0.94, 0.94 (p < 0.01) の高度の相関が存在した. 左室壁運動の状態をSPECTとLVGで対比したが, 両者のwall motion scoreはr = 0.84 (p < 0.01) と高度の相関を示し, プラナー法に比し有意に優れていた.
Practice臨床医学：一般
KeywordsGated cardiac blood pool SPECT, Left ventricular volume, Left ventricular wall motion, Wall motion score.
English
TitleAsessment of Left Ventricular Function by Gated Cardiac Blood-Pool Emission Computed Tomography Using a Rotating Gamma Camera
SubtitleOriginal Articles
AuthorsMichihiro NARITA*, Tadashi KURIHARA*, Kenichi MURANO*, Masahisa USAMI*, Minoru HONDA**
Authors(kana)
Organization*Department of Internal Medicine, Sumitomo Hospital, **Department of Nuclear Medicine, Sumitomo Hospital
JournalThe Japanese Journal of nuclear medicine
Volume28
Number1
Page51-61
Year/Month1991/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To elucidate the usefulness of gated cardiac blood-pool single photon emission CT (SPECT) with Tc-99m for the evaluation of left ventricular (LV) global and regional functions, 18 patients with coronary artery disease were studied. Thirty-two gated projection images were obtained over 360-degree at 16 frames per cardiac cycle. As LV volume was calculated by integrating the numbers of voxels which constituted LV and multiplying by the volume of a single voxel (0.1143ml), we performen phantom studies to determine the appropriate cut-off level to detect LV outline. These cut-off levels were affected by the background activity and organ volume itself. So we constructed Volume-Cut-Level-Curve at each background activity. In clinical studies, short axis images which constituted LV were selected and provisional LV volumes were calculated at the cut-off levels of 45, 50 and 55%. These volumes were plotted on the Volume-Cut-Level-Curve and the true cut-off levels were obtained to calculate LV end-diastolic or end-systolic volume (EDV, ESV). The cut-off levels were different at every patient and ED or ES. EDV, ESV and LV ejection fraction obtained by SPECT were correlated well with those obtained by contrast ventriculography (LVG) (r = 0.89, 0.94, 0.94 each, p < 0.01). For the LV wall motion analysis, LVGs obtained at two projections were compared with SPECT or gated cardiac blood-pool planar imaging (Planar) in 5 segments. In addition to visual comparison, wall motion scores (WMS) based on the degree of wall motion abnormality were calculated in each segment. Correlation of WMS between LVG and SPECT (r = 0.84) was significantly (p < 0.01) superior to that between LVG and Planar (r = 0.62). Especially in SPECT, wall motion analyses at septal and infero-postrior segments were superior to those in Planar. Although gated SPECT requires relatively long time to perform, it is a useful method to detect LV global and regional functions.
PracticeClinical medicine
KeywordsGated cardiac blood pool SPECT, Left ventricular volume, Left ventricular wall motion, Wall motion score.

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