| Japanese |
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| Title | 運動負荷Radionuclide VentriculographyによるSilent Myocardial Ischemiaの検討 - 非梗塞群と梗塞群の比較 - |
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| Subtitle | 原著 |
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| Authors | 佐藤隆行*, 目黒光彦*, 殿岡一郎*, 政金生人*, 竹石恭和*, 立木楷*, 駒谷昭夫** |
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| Authors(kana) | |
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| Organization | *山形大学医学部第一内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 1 |
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| Page | 43-50 |
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| Year/Month | 1991/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」運動負荷radionuclide ventriculography (RNV) を用いて, silent myocardial ischemia (SMI) の左室収縮能を検討した. 対象は運動負荷RNV施行時心電図上虚血性変化を示し, 心臓カテーテル検査にて冠動脈近位部に有意狭窄病変を認めた61例に限定した. SMIの運動負荷時左室収縮能の低下は, 胸痛群に比較し軽度であった (ejection fractionの運動時と安静時の差 : ΔEF ; P < 0.05, systolic blood pressure / end-systolic volumeの運動時と安静時の比 : SP / ESV (ex / rest) ; p < 0.05). さらに症例を非梗塞群と梗塞群にわけて, それぞれSMI群と胸痛群とを比較検討した. 非梗塞群では運動負荷時左室収縮能低下の差がさらに明らかになったが (ΔEF ; p < 0.01, SP / ESV (ex / rest) ; p < 0.01), 梗塞群では両者の間に差を認めなかった. 非梗塞群におけるSMIはより軽度の心筋虚血であり, 梗塞群におけるSMIは心筋虚血の程度以外の要因によるものと考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise radionuclide ventriculography, Silent myocardial ischemia. |
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| English |
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| Title | Evaluation of Silent Myocardial Ischemia by Exercise Radionuclide Ventriculography : Comparison between Patients with and without Old Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Takayuki SATO*, Mitsuhiko MEGURO*, Ichiro TONO-OKA*, Ikuto MASAKANE*, Yasuchika TAKEISHI*, Kai TSUIKI*, Akio KOMATANI** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, **Department of Radiology, Yamagata University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 1 |
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| Page | 43-50 |
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| Year/Month | 1991/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] We evaluated left ventricular systolic function during exercise in patients with silent or symptomatic myocardial ischemia by radionuclide ventriculography (RNV). The subjects were consisted of 61 patients who had evidence of myocardial ischemia during exercise RNV defined as positive exercise electrocardiographic changes and angiographically documented coronary artery disease. The patients without angina during exercise (SMI) had less exercise-induced left ventricular systolic dysfunction than patients with angina (CP) (change in ejection fraction during exercise : ΔEF ; -1 +- 13 vs -6 +- 10%, p < 0.05, systolic blood pressure / end-systolic volume in exercise divided by systolic blood pressure / end-systolic volume in rest : SP / ESV (ex / rest) ; 1.1 +- 0.6 vs 0.8 +- 0.3, p < 0.05). The 61 patients were divided into two groups, that is, those with and without old myocardial infarction (OMI), and we compared the degree of left ventricular systolic dysfunction during exercise between SMI and CP by RNV in each group. In patients without OMI, SMI had less exercise-induced left ventricular dysfunction than CP (ΔEF ; 1 +- 12 vs -10 +- 8%, p < 0.01, SP / ESV (ex / rest) ; 1.1 +- 0.6 vs 0.7 +- 0.2, p < 0.01). However, there were no differences between SMI and CP with OMI. In conclusion, it was thought that SMI without OMI was less degree of myocardial ischemia, and that SMI with OMI was potentially caused by some factors except for the degree of myocardial ischemia. |
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| Practice | Clinical medicine |
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| Keywords | Exercise radionuclide ventriculography, Silent myocardial ischemia. |
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