| Japanese |
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| Title | 慢性期心筋梗塞における安静時Tl-201肺内取り込みの臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 田中健*, 相澤忠範*, 加藤和三*, 岡本淳*, 北原公一**, 鈴木紳**, 小船井良夫**, 広沢弘七郎**, 上田英雄** |
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| Authors(kana) | |
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| Organization | *心臓血管研究所, **榊原記念病院 |
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| Journal | 核医学 |
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| Volume | 28 |
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| Number | 1 |
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| Page | 35-41 |
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| Year/Month | 1991/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」臨床的に安定した慢性期心筋梗塞159例を対象としてTl-201肺内取り込みの病態を検討した. 定量的評価は正面像におけるTl-201肺内取り込み最高カウントとTl-201心筋内取り込み最高カウントとの比 (lung heart ratio : LHR) を用いた. mPw = 2.7 + 10.5 LHR (r = 0.52, n = 102, p < 0.001) EF = 84.9 - 52.2 LHR (r = -0.61, n = 159, p < 0.001) mPw : 平均肺動脈楔入圧, EF : 左心駆出率 Tl-201肺内取り込みは肺動脈楔入圧の上昇や左心駆出率の低下と共に下肺野から増大し, 時には心筋像と同程度以上となることが示された. しかし急性期心筋梗塞例と比較すると同じようなTl-201肺内取り込みであっても肺血行動態の悪化程度はより軽度であった. Tl-201肺内取り込みは心不全における肺鬱血の定量的評価方法として有用と考えられた. 肺血行動態と密接な関係を有するが, これ以外の因子も関与していることが示された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Tl-201 lung uptake, Congestive heart failure. |
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| English |
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| Title | Thallium-201 Lung Uptake in Patients with Chronic Phase of Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Takeshi TANAKA*, Tadanori AIZAWA*, Kazuzo KATOU*, Kiyoshi OKAMOTO*, Kouichi KITAHARA**, Shin SUZUKI**, Yoshio OBUNAI**, Koushichiro HIROSAWA**, Hideo UEDA** |
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| Authors(kana) | |
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| Organization | *The Cardiovascular Institute, **Sakakibara Memorial Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 28 |
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| Number | 1 |
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| Page | 35-41 |
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| Year/Month | 1991/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To study pathophysiological significance of Tl-201 lung uptake in coronary artery disease Tl-201 lung uptake was studied in 159 patients with chronic phase of myocardial infarction. Tl-201 lung uptake images were collected after rest Tl-201 myocardial imaging. Tl-201 lung uptake was estimated by comparing maximal lung counts with maximal myocardial counts (thallium lung heart ratio : LHR), Good correlation between LHR and mean pulmonary artery wedge pressure (mPw) and between LHR and left ventricular ejection fraction (EF) were obtained, (mPw = 2.7 + 10.5 LHR r = 0.52 n = 102, p < 0.001, EF = 84.9 - 52.2 LHR r = -0.61 n = 159, p < 0.001). It was noted that Tl-201 did not accumulate uniformly through the lung field and usually maximal Tl-201 lung uptake was noted at the basal zone of the right lung. Tl-201 lung uptake in the upper zone of the right lung increased in proportion to the hemodynamic deterioration. Interesting differences were noted between Tl-201 lung uptake in patients with chronic phase of myocardial infarction and that in patients with acute phase of myocardial infarction. The prognosis and clinical status of patients with markedly increased Tl-201 lung uptake (LHR > 0.8) in chronic phase were more excellent than the patients with similar Tl-201 lung uptake in acute phase. Hemodynamic prameters in patients with markedly increased Tl-201 lung uptake (LHR >= 0.8) in chronic phase were significantly better than in those in acute phase. Patients with markedly increased Tl-201 lung uptake (LHR > 0.8) in acute phase showed improvement of Tl-201 lung uptake in convalescent phase. Close relation between Tl-201 lung uptake and pulmonary congestion was noted. There might be many factors determing Tl-201 lung uptake in addition to hemodynamic parameters. Tl-201 lung uptake is useful for quantitative estimation of congestive heart failure, father study will be necessary to clarify the relation between Tl-201 lung uptake and extravascular pulmonary water. |
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| Practice | Clinical medicine |
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| Keywords | Tl-201 lung uptake, Congestive heart failure. |
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