| Japanese |
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| Title | 頭蓋骨早期癒合症の手術前後における123I-IMP-SPECT像の検討 |
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| Subtitle | 原著 |
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| Authors | 佐藤始広*, 石川演美**, 榎本貴夫***, 武田徹**, 吉澤卓***, 能勢忠男*** |
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| Organization | *筑波大学付属病院放射線科, **臨床医学系放射線科, ***脳神経外科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1411-1418 |
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| Year/Month | 1990/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」頭蓋骨早期癒合症の小児13例に手術前後で123I-IMP脳血流シンチグラフィを施行し比較検討した. 手術前の検査では13例中8例 (62%) に血流低下を認めた. 短頭蓋7例では4例 (57%) に, 前頭葉, 後頭葉, 小脳のいずれかの部位に血流低下を認めた. また舟状頭蓋2例と斜頭蓋の1例ではいずれも片側大脳半球 (特に側頭葉を中心とする) の血流低下が認められた. 一方, Crouzon病の2例では正常の血流分布を示したが, Apert病の1例では両側前頭葉, 小脳, および左後頭葉の血流低下を認めた. 同時期に施行されたCTではいずれの症例においても脳実質の異常は認められなかった. 手術後の検査ではこの8例のうち6例 (75%) では血流低下の軽減ないし消失を認めた. 123I-IMP脳血流シンチグラフィは, 本症の局所脳血流障害の評価および術後の機能回復の一指標として有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Craniosynostosis, N-isopropyl-p-[123I]iodoamphetamine (123I-IMP), Single photon emission computed tomography (SPECT), Regional cerebral blood flow (rCBF). |
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| English |
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| Title | The Study of I-123-IMP-SPECT before and after Surgery for Craniosynostosis |
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| Subtitle | Original Articles |
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| Authors | Motohiro SATOH*, Nobuyoshi ISHIKAWA**, Takao ENOMOTO***, Tohru TAKEDA**, Takashi YOSHIZAWA***, Tadao NOSE*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, University Hospital of Tsukuba, **Department of Radiology, Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1411-1418 |
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| Year/Month | 1990/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Single photon emission computed tomography with N-isopropyl-p-[I-123]iodoamphetamine was performed in 13 cases of craniosynostosis before and after surgery. Of 13 cases, 8 cases (62%) showed focal low perfusion area on preoperative study. Four of seven cases (57%) with brachycephaly showed low perfusion areas in either of frontal lobes, occipital lobes, and cerebellum. Besides, two patients with scaphocephaly and one with plagiocephaly showed low perfusion area in unilateral cerebral hemisphere. Two Crouzon disease cases showed no focal low perfusion area, but an Apert disease showed low perfusion areas in both frontal lobes, cerebellum, as well as left occipital lobe. Corresponding CT and MRI showed no focal abnormality in any of these cases. These low perfusion areas were diminished or disappeared after surgical treatment in 6 cases (75%). We conclude that the I-123-IMP-SPECT is considered to be a useful index for the evaluation of functional recovery after surgery in cases with craniosynostosis. |
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| Practice | Clinical medicine |
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| Keywords | Craniosynostosis, N-isopropyl-p-[123I]iodoamphetamine (123I-IMP), Single photon emission computed tomography (SPECT), Regional cerebral blood flow (rCBF). |
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