| Japanese |
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| Title | 因子分析を用いたタリウムによる甲状腺検査での腫瘍分離描画の試み |
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| Subtitle | 原著 |
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| Authors | 油井信春*, 戸川貴史*, 小圷正木*, 木下富士美*, 秋山芳久**, 嶋田文之*** |
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| Organization | *千葉県がんセンター核医学診療科, **物理室, ***頭頸科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1385-1392 |
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| Year/Month | 1990/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」組織診断の得られている38人の甲状腺腫瘍または類似疾患患者において因子分析 (Factor analysis) をタリウム甲状腺イメージングに応用して腫瘍と正常部を異なる機能として分離抽出することを試みた. 38人の患者のうち28例で病巣を正常甲状腺から分離描画することができた. 従来より腫瘍診断法として用いられているdelayed scanと比較したが同等または上回る結果であり, 他の方法では検出できなかった1cm以下の腫瘍も描画が可能であった. 抽出された病巣に相当する機能曲線は濾胞癌と乳頭癌で異なる傾向を示したが曲線のパターンから鑑別できるまでには至らなかった. しかし正常甲状腺とは明らかに異なるパターンを示した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Factor analysis, Thallium-201 chloride, Thyroid tumor. |
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| English |
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| Title | Factor Analysis in Thallium-201 Chloride Thyroid Studies |
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| Subtitle | Original Articles |
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| Authors | Nobuharu YUI*, Takashi TOGAWA*, Masaki KOAKUTSU*, Fujimi KINOSHITA*, Yoshihisa AKIYAMA**, Fumiyuki SHIMADA*** |
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| Authors(kana) | |
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| Organization | *Division of Nuclear Medicine, Chiba Cancer Center Hospital, **Division of Radiation Physics, Chiba Cancer Center Hospital, ***Division of Head and Neck Surgery, Chiba Cancer Center Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1385-1392 |
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| Year/Month | 1990/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Factor analysis was applied to thyroid thallium-201 imaging to get separated image of tumor from normal thyroid tissue. Thirty-eight patients with various thyroid tumors which were histologically confirmed were included in this study. Following intravenous injection of 111 MBq (3mCi) of 201Tl chloride, thyroid images in 64 frames were taken for 30 to 60 minutes using Toshiba gamma camera system and data were analyzed by 2 or 3 factor analysis. In 28 of 38 patients separated images of the lesions from normal thyroid were obtained and time-activity curves of various shapes corresponding to the lesions were also obtained. When the curves were classified into 3 groups according to their shapes : increasing, flat and decreasing, follicular carcinoma did not show increasing shape whilst neither of papillary carcinoma, squamous cell carcinoma and anaplastic carcinoma showed decreasing shape. The shapes of the curves were thought to be reflected in clearance of the agent from the lesions. Factor analysis in 201Tl chloride thyroid scan provided separated image of tumor from normal thyroid gland automatically and the obtained curves corresponding to the lesions provided information for estimating the characteristics of thyroid tumors. |
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| Practice | Clinical medicine |
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| Keywords | Factor analysis, Thallium-201 chloride, Thyroid tumor. |
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