| Japanese |
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| Title | Tl-201負荷心筋シンチグラム, 心動態シンチグラムによる糖尿病患者の心合併症の検討 |
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| Subtitle | 原著 |
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| Authors | 宮下岳夫*, 笠井龍太郎*, 池部伸彦*, 永井義一*, 山澤いく宏*, 伊吹山千晴*, 能登谷洋子** |
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| Organization | *東京医科大学第二内科, **第三内科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1369-1375 |
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| Year/Month | 1990/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」糖尿病患者における潜在性心病変の診断を目的に, 心愁訴のない糖尿病患者を, 高血圧の合併がなく心電図の正常な (DM) 群, 高血圧を合併する (HT) 群, 心電図上心筋障害が認められる (MD) 群, 両者を合併する (HT + MD) 群の4群に分け, Tl-201負荷心筋シンチグラムおよび心動態シンチグラムを施行し, 比較検討した. SPECT陽性率は, DM群83人中23人 (27.7%), HT群30人中9人 (30.0%), MD群12人中6人 (50.0%), HT + MD群17人中12人 (70.6%) で, DM群およびHT群に比し, HT + MD群は有意に高かった (p < 0.01, p < 0.01). 心動態シンチグラムの各指標では, HT + MD群において, 正常対象群に比し, 1/3FFおよび, PFRの有意な低下とTPFの有意な延長が認められた (p < 0.001, p < 0.05, p < 0.05). すなわち, 糖尿病患者では高血圧と心筋障害の合併により, 左室急速流入障害とSPECT上陽性所見を高率に示した. 以上より, 糖尿病患者では心愁訴がなくとも潜在性心病変が高率に存在し, 特に高血圧と心筋障害両者の合併により顕著になることを, 負荷心筋シンチグラムおよび, 心動態シンチグラムより明らかにした. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise myocardial imaging, Blood pool scintigram, Diabetes mellitus, Cardiac complications. |
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| English |
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| Title | Evaluation of Latent Cardiac Disease in Diabetic Patients with Tl-201 Exercise Myocardial Scintigram and Blood Pool Scintigram |
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| Subtitle | Original Articles |
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| Authors | Takeo MIYASHITA*, Ryutaro KASAI*, Nobuhiko IKEBE*, Yoshikazu NAGAI*, Ikuhiro YAMASAWA*, Chiharu IBUKIYAMA*, Yoko NOTOYA** |
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| Authors(kana) | |
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| Organization | *Second and **Third Departments of Internal Medicine, Tokyo Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 12 |
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| Page | 1369-1375 |
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| Year/Month | 1990/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To find latent heart disease in diabetic patients, 142 diabetic patients were divided into 4 groups : 1) No hypertension and normal ECG (DM group) ; 2) Hypertension recognized clinically (HT group) ; 3) Myocardial damage on ECG (MD group) 4) group associated with the previous 2 (HT + MD group). In all groups Tl-201 exercise myocardial scintigrams and blood pool scintigrams were taken for comparative analysis. Positive rates of SPECT were 27.7% (23/83) in the DM group, 30.0% (9/30) in the HT group, 50.0% (6/12) in MD group, and 70.6% (12/17) in the HT + MD group. The rate in the HT + MD group was significantly higher than in that of the DM and HT groups (p < 0.001, p < 0.01). Blood pool scintigrams revealed that in the HT + MD group, as compared with the normal control group, both 1/3 FF and PFR were significantly depressed, in addition to significant TPF prolongation in the formmer (p < 0.001, p < 0.05, p < 0.05). These findings suggest that in diabetic patients hypertension and myocardial damage would lead to a high incidence of abnormality in SPECT and left ventricular rapid filling dysfunction. This indicate a high incidence of latent cardiac disease which can be recognized in diabetic patients by stress myocardial and blood pool scintigrams. |
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| Practice | Clinical medicine |
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| Keywords | Exercise myocardial imaging, Blood pool scintigram, Diabetes mellitus, Cardiac complications. |
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