| Japanese |
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| Title | 心筋viability評価における安静時201Tl心筋シンチグラフィの意義 |
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| Subtitle | 《原著》 |
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| Authors | 大和田憲司*, 渡辺直彦*, 菅家道人*, 斎藤富善*, 浅倉司*, 粟野直行*, 内田立身*, 丸山幸夫*, 斎藤恒儀**, 上遠野栄一***, 鈴木重文**** |
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| Authors(kana) | |
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| Organization | *福島県立医科大学第一内科, **米沢市立病院循環器科, ***太田西ノ内病院循環器科, ****福島労災病院循環器科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 11 |
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| Page | 1291-1299 |
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| Year/Month | 1990/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」心筋viabilityを精度よく評価するために, 虚血性心疾患65症例を対象に従来の運動負荷201Tl心筋シンチグラフィのみでなく, 別の日に安静時201Tl心筋シンチグラフィを追加して, その臨床的意義を検討した. 極座標図法を用いた解析で, 非梗塞虚血領域の83%, 梗塞領域の39%に負荷時再分布を認めた. 負荷4時間後Tl像と安静時Tl像を比較すると, 非梗塞虚血領域はほとんど不変だったのに対し, 梗塞領域の48%は安静時Tl像で改善所見を認めた. 負荷時再分布のなかった心筋梗塞例のうち安静時Tl像で改善を示した群は, 負荷4時間後の%Tl uptakeが高値(59±10%)で, washout rate(39±10%)が低値であった. 以上より, 運動負荷201Tl心筋シンチグラフィでみられる再分布は, 虚血領域の心筋viabilityの評価に有用である. しかし, 梗塞領域では%Tl uptakeが40%以上の場合, 安静時201Tl心筋シンチグラフィを追加する必要があると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 myocardial SPECT, redistribution, coronary artery disease, myocardial viability, resting 201Tl scintigraphy. |
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| English |
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| Title | Assessment of Myocardial Viability by Resting 201Tl SPECT Image |
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| Authors | Kenji OWADA*, Naohiko WATANABE*, Michito KANBE*, Tomiyoshi SAITOH*, Tsukasa ASAKURA*, Naoyuki AWANO*, Tatsumi UCHIDA*, Yukio MARUYAMA*, Tsuneyoshi SAITOH**, Eiichi KATOHNO***, Shigefumi SUZUKI**** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Fukushima Medical College, **Department of Cardiovascular Medicine, Yonezawa General Hospital, ***Department of Cardiovascular Medicine, Ohta-nishinouchi Hospital, ****Department of Cardiovascular Medicine, Fukushima Rohsai Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 11 |
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| Page | 1291-1299 |
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| Year/Month | 1990/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | The aim of this study was to assess whether resting 201Tl scintigraphy is superior in detecting viable myocardium than previous conventional methods. We performed not only stress 201Tl SPECT but also resting 201Tl SPECT within one month in 65 patients with coronary artery disease. Resting 201Tl images were quantitatively compared with 4 hour late images of stress study using a polar map. In stress study, redistribution was recognized on 83 (25/30) of non-MI SEGs with perfusion defect in the stress 201Tl image, and on 39% (18/46) of infarcted SEGs. The agreement of resting 201Tl study with 4 hour late images of stress study was shown on 93% (28/30) of non-MI SEGs and on 52% (24/46) of MI SEGs. The increased uptake of 201Tl in resting study, however, was found on 13 (46%) of 28 MI SEGs showing fixed defects in stress study. In stress delayed image with fixed defect, the %Tl uptake of improved SEGs was higher than that of unchanged SEGs (59+-10% vs 48+-11%; p>0.05). There was no viable myocardium which had %Tl uptake less than 40% at stress delayed image. In conclusion, the resting 201Tl imaging will give an important information as for the myocardial viability showing fixed defects, if more than 40% Tl uptake is observed. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 myocardial SPECT, redistribution, coronary artery disease, myocardial viability, resting 201Tl scintigraphy. |
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