Japanese
Title因子分析法の運動負荷心プールシンチグラフィへの応用 : 各種functional imageとの比較
Subtitle《原著》
Authors松成一朗*, 分校久志*, 中嶋憲一*, 滝淳一*, 四位例靖*, 久田欣一*
Authors(kana)
Organization*金沢大学医学部核医学科
Journal核医学
Volume27
Number11
Page1265-1272
Year/Month1990/11
Article原著
Publisher日本核医学会
Abstract「要旨」心電図同期心プールシンチグラフィにおいて因子分析法を中心とした各種functional imageについて比較検討した. 因子分析には左室のみをマスキングにより抽出する解析法(因子分析左室法)を用いた. この因子分析左室法における3因子分析では生理的意味づけの不能な因子がしばしば出現し, 2因子分析の方が良好な結果が得られた. 本法による虚血性心疾患患者を対象とした壁運動評価の成績は, シネモード表示にて壁運動異常を示した20例中17例, 壁運動正常であった28例全例にて所見が一致し(感度85%, 特異度100%), 他のfunctional image(EF像, SV像, 位相像)に比べ優れていた. 更に運動負荷心プールシンチグラフィに応用することにより, 各因子画像の変化から壁運動異常の検出が容易になった. 本法は比較的簡便であり日常の臨床にも適している.
Practice臨床医学：一般
KeywordsGated blood pool study, Functional image, Factor analysis, Ischemic heart disease.
English
TitleEvaluation of Factor Analysis and Other Functional Images in Exercise Gated Blood-Pool Study
Subtitle- Original Articles -
AuthorsIchiro MATSUNARI, Hisashi BUNKO, Kenichi NAKAJIMA, Junichi TAKI, Yasushi SHIIRE, Kinichi HISADA
Authors(kana)
OrganizationThe Department of Nuclear Medicine, School of Medicine, Kanazawa University
JournalThe Japanese Journal of nuclear medicine
Volume27
Number11
Page1265-1272
Year/Month1990/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractFactor analysis, a new method of functional imaging, has been applied to cardiovascular nuclear medicine. Because of the difficulty of its interpretation, it has not been popular as a method for detecting abnormal wall motion. The purpose of this study was to evaluate the usefulness of factor analysis in exercise gated blood-pool study in patients with ischemic heart disease. In our factor analysis, left ventricular region of interest (LVROI) was extracted to exclude the surrounding radioactivities. The new method was compared with 1) the conventional factor analysis using whole region (whole ROI method), and with 2) the other functional images, i.e. stroke volume, ejection fraction and phase images. At first we tried 3-factor analysis of the LVROI method, which resulted in many uninterpretable factors. Whereas in 2-factor analysis no uninterpretable factors were extracted. In comparison with cine-mode display, the LVROI method with 2-factor analysis showed the best sensitibity (85%) and specificity (100%). In exercise gated blood-pool study, it became easier to detect abnormal wall motion by comparing the factor image at exercise with resting image. In conclusion, the 2-factor analysis using the LVROI method greatly improved the limitation of conventional factor analysis, and will be useful in detecting wall motion abnormality in patients with ischemic heart disease.
PracticeClinical medicine
KeywordsGated blood pool study, Functional image, Factor analysis, Ischemic heart disease.

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