| Japanese |
|---|
| Title | I-123 IMP SPECTによる橋描出の検討 |
|---|
| Subtitle | 《原著》 |
|---|
| Authors | 蓑島聡*, 椎名丈城**, 山上岩男***, 宇野公一*, 岡田淳一*, 山浦晶****, 安西好美*, 伊丹純*, 内田佳孝**, 有水昇*, 北方勇輔**, 磯部勝見*** |
|---|
| Authors(kana) | |
|---|
| Organization | *千葉大学医学部放射線科, **君津中央病院放射線科, ***脳神経外科, ****千葉大学医学部脳神経外科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 27 |
|---|
| Number | 11 |
|---|
| Page | 1255-1264 |
|---|
| Year/Month | 1990/11 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」I-123 IMP SPECTによる橋描出の程度, 原疾患との関係などについて検討を行った. 対象は脳梗塞46例, その他の脳血管障害25例, 脳腫瘍28例, 正常19例の計118例である. I-123 IMPは111 MBq(3 mCi)を用い, 静注約30分後から単検出器回転型SPECTにより撮像を行った. 橋描出は外眼角耳孔線に平行に再構成したフィルム上の横断像にて視覚的にgrade 1(不明瞭)〜3(明瞭)の3段階に分類した. その結果, 疾患群では有意に橋描出が低下する傾向にあり, 脳幹病変を認めた6症例では, 4症例がgrade 1, 2症例がgrade 2と評価された. 一方テント上病変に伴うCrossed cerebellar diaschisis(CCD)を認めた29症例では, 橋集積低下の頻度が有意に高い傾向にあった. I-123 IMP SPECTでは, 脳幹病変が集積低下として示されるとともに, CCD陽性例での橋集積低下は, 橋核レベルでの血流・代謝の低下が関与する可能性が示唆された. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | I-123 IMP, SPECT, pons, crossed cerebellar diaschisis, brain infarction. |
|---|
| English |
|---|
| Title | Evaluation of Pontine Visualization with Single Photon Emission Computed Tomography using N-isopropyl-p-(I-123) iodoamphetamine in Normal and Pathological Cases |
|---|
| Subtitle | - Original Articles - |
|---|
| Authors | Satoshi MINOSHIMA*, Takeki SHIINA**, Iwao YAMAGAMI***, Kimiichi UNO*, Junichi OKADA*, Akira YAMAURA****, Yoshimi ANZAI*, Jun ITAMI*, Yoshitaka UCHIDA**, Noboru ARIMIZU*, Yusuke KITAKATA**, Katsumi ISOBE*** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Chiba University, School of Medicine, **Department of Radiology, Kimitsu Central Hospital, ***Department of Neurosurgery, Kimitsu Central Hospital, ****Department of Neurosurgery, Chiba University, School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 27 |
|---|
| Number | 11 |
|---|
| Page | 1255-1264 |
|---|
| Year/Month | 1990/11 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | Pontine visualization with single photon emission computed tomography (SPECT) using N-isopropyl-p-[I-123]iodoamphetamine (I-123 IMP) was evaluated in 99 cases including 46 cases of brain infarction, 25 of other cerebrovascular disorders and 28 of brain tumor and in 19 normal subjects. In each case, SPECT using a rotating gamma camera was started at 30 minutes after intravenous administration of 111 MBq of I-123 IMP. Transverse images were reconstructed parallel to the cantho-meatal line and displayed on films. Pontine visualization was visually classified into three grades: high radioactive accumulation confined to the pons with clear contour (Grade 3), faint accumulation with indistinct contour in the pontine region (Grade 1), the pontine accumulation was identified but its activity was less significant (Grade 2). The results showed that grade of the pontine accumulation was lower in pathological cases compared to normal subjects. Six cases with brain stem lesion demonstrated pontine accumulation of grade 1 in 4 case and of grade 2 in 2 cases. Lower grade was also revealed in 29 cases with crossed cerebellar diaschisis (CCD). No significant correlation was observed between classified grade of pontine accumulation and maximum counts of reconstructed images. We concluded that SPECT could detect brain stem lesions and that lower accumulation in pons with CCD positive cases was thought to partially reflect the reduced blood flow and metabolism in the pontine nuclei. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | I-123 IMP, SPECT, pons, crossed cerebellar diaschisis, brain infarction. |
|---|