| Japanese |
|---|
| Title | 123I-IMP SPECTによる小児特発性てんかん患者の検討 |
|---|
| Subtitle | 《原著》 |
|---|
| Authors | 原正史*, 下村修*, 古嶋昭博*, 伊豆永浩志*, 冨口静二*, 広田嘉久*, 高橋睦正*, 多久肇一**, 三池輝久** |
|---|
| Authors(kana) | |
|---|
| Organization | *熊本大学医学部放射線科, **発達小児科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 27 |
|---|
| Number | 11 |
|---|
| Page | 1239-1245 |
|---|
| Year/Month | 1990/11 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」経過観察中の小児特発性てんかん患者18例にIMP SPECT, CT, MRIを行い比較検討をおこなった. 各種画像診断における異常所見率はSPECT 50%, CT 11%, MRI 13%であり, 特にSPECTにおいて高く, 異常例では全例低血流を示したが, EEG上の焦点とは低い一致率であった. 入院治療を試みた例において入院前後の発作頻度の変化をSPECT所見と対比検討したが, SPECT上異常集積を認める例では発作のコントロールが比較的困難であった. 同時に知能発育遅滞との関係をみたが, SPECT上異常集積を認める例では高率に知能発育遅滞が認められており, SPECTで認められる血流の低下が発育途上の小児の脳に影響を与えていることが推測された. 今後IMP SPECTは小児てんかんの診断, 治療に広く応用されることが期待される. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Epilepsy, Single Photon Emission Computed Tomography (SPECT), N-isopropyl-p[123I]iodoamphetamine. |
|---|
| English |
|---|
| Title | 123I-IMP Single Photon Emission Computed Tomography (SPECT) Study in Childhood Epilepsy |
|---|
| Subtitle | - Original Articles - |
|---|
| Authors | Masafumi HARA*, Osamu SHIMOMURA*, Akihiro KOJIMA*, Hiroshi IZUNAGA*, Seiji TOMIGUCHI*, Yoshihisa HIROTA*, Keiichi TAKU**, Teruhisa MIIKE**, Mutsumasa TAKAHASHI* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Kumamoto University School of Medicine, **Department of Child development,, Kumamoto University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 27 |
|---|
| Number | 11 |
|---|
| Page | 1239-1245 |
|---|
| Year/Month | 1990/11 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | N-isopropyl-p[123I]-iodoamphetamine (IMP) single photon emission computed tomography (SPECT), X-ray computed tomography (X-CT) and magnetic resonance imaging (MRI) were performed in 18 children with idiopathic seizures. In children with idiopathic seizures SPECT identified abnormal lesions in the highest rate (50%) compared with X-CT (11%) and MRI (13%), but the findings of SPECT poorly correlated with the foci on electroencephalography (EEG). Idiopathic epilepsy with abnormal uptake on SPECT was refractory to medical treatments and frequently associated with mental and/or developmental retardation. Perfusion defects identified on SPECT probably influenced the development of the brains in children. IMP SPECT is useful in the diagnosis and medical treatment in children with seizures. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Epilepsy, Single Photon Emission Computed Tomography (SPECT), N-isopropyl-p[123I]iodoamphetamine. |
|---|