| Japanese |
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| Title | 133Xeクリアランス法を用いた下腿皮膚末梢循環血圧の測定 |
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| Subtitle | 《原著》 |
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| Authors | 伊藤秀稔*, 田中早苗*, 島田孝夫*, 磯貝行秀*, 森豊**, 川上憲司** |
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| Organization | *東京慈恵会医科大学第三内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 10 |
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| Page | 1141-1145 |
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| Year/Month | 1990/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」133Xeクリアランス法を用いた下腿の皮膚における末梢循環血圧の新しい測定方法を開発し, 50名の健常者と86名の糖尿病患者, うち16名の糖尿病性壊疽合併例を対象に下肢の前脛骨部における皮膚末梢循環血圧を測定した. 健常者群の皮膚末梢循環血圧は41.9±8.6cmH2O, 糖尿病性壊疽非合併例群の皮膚末梢循環血圧は30.2±12.7cmH2O, 糖尿病性壊疽合併例群の皮膚末梢循環血圧は19.4±10.3cmH2Oとp<0.01で壊疽合併例がもっとも低値であった. 糖尿病性壊疽の発症機序として糖尿病性自律神経障害による皮下の動静脈吻合血管の持続的な開大のために皮膚への有効血流量減少が起こり, その結果皮膚の末梢循環血圧が低値となって, そのため僅かな外力でも容易に血流が遮断されてしまい末梢組織の虚血が起こり壊疽に陥ると考えられ, 本検査法は末梢循環動態を的確に反映した検査法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 133Xe clearance method, Skin peripheral perfusion pressure, Diabetes mellitus, Diabetic gangrene, Diabetic neuropathy. |
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| English |
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| Title | Skin Peripheral Perfusion Pressure (SPPP) in the Leg Using a Technique of 133Xe Clearance Method |
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| Subtitle | - Original Articles - |
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| Authors | Hidetoshi ITO*, Sanae TANAKA*, Takao SHIMADA*, Yukihide ISOGAI*, Yutaka MORI**, Kenji KAWAKAMI** |
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| Authors(kana) | |
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| Organization | *The Third Department of Internal Medicine, **Department of Radiology, Jikei University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 10 |
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| Page | 1141-1145 |
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| Year/Month | 1990/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We developed a new technique for measuring skin peripheral perfusion pressure (SPPP) in the leg by 133Xe clearance method and studied the SPPP in 50 normal volunteers and 86 diabetic patients, including 16 diabetics with gangrene. The SPPP in normal subjects, diabetics without gangrene and diabetics with gangrene were 41.9+-8.6 cmH2O, 30.2+-12.7 cmH2O and 19.4+-10.3 cmH2O, respectively. Our result revealed that the SPPP in diabetics with gangrene was significantly lowest in three groups. The decrease of the SPPP in the diabetics may be due to the steal phenomenon of the blood flow through the abnormally dilated arteriovenous shunt vessels caused by the diabetic neuropathy. The measurement of the SPPP is very useful to assess the impairment of peripheral circulation. |
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| Practice | Clinical medicine |
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| Keywords | 133Xe clearance method, Skin peripheral perfusion pressure, Diabetes mellitus, Diabetic gangrene, Diabetic neuropathy. |
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