| Japanese |
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| Title | 虚血性心疾患診断における左室機能指標peak systolic pressure / left ventricular end-systolic volume (PSP / LVESV) の有用性と限界 - radionuclide ventriculographyを用いた検討 - |
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| Subtitle | 《原著》 |
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| Authors | 小山孝夫 |
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| Organization | 三重大学医学部第一内科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 10 |
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| Page | 1119-1127 |
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| Year/Month | 1990/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」運動負荷RNVを用い, 虚血性心疾患の診断における左室機能指標としてのpeak systolic pressure/left ventricular end-systolic volume(PSP/LVESV)の有用性と限界について評価した. 1)労作性狭心症26例を対象とした検討では, 多段階運動負荷試験による心筋虚血の検出に関して, LVEF, LVESV, PSP/LVESVの変化をその指標とした場合, 軽症狭心症例においても胸痛および心電図異常が出現する以前にその異常が出現したが, 各指標間には鋭敏さに差はなかった. 2)虚血性心疾患112例, 正常冠動脈例55例での検討では, 左室機能指標としてのΔEF, ΔESV, PSP/LVESVの変化(ERPV)による心筋虚血の検出率は, sensitivityは96%, 95%, 96%とほぼ同等であったが, specificityは91%, 93%, 98%, overall accuracyは95%, 94%, 96%と, PSP/LVESVによるものが最も良好であった. しかしこれらはglobalな指標であるため, 診断精度の向上には局所指標を加味した総合判定が必要であると考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc radionuclide ventriculography, ergometer exercise, coronary heart disease, peak systolic pressure/left ventricular end-systolic volume (PSP/LVESV). |
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| English |
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| Title | Utility of Peak Systolic Pressure / Left Ventricular End-systolic Volume (PSP / LVESV) Ratio in Diagnosis of Coronary Artery Disease -Assessment by Radionuclide Ventriculography - |
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| Subtitle | - Original Articles - |
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| Authors | Takao KOYAMA |
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| Authors(kana) | |
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| Organization | The First Department of Internal Medicine, Mie University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 10 |
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| Page | 1119-1127 |
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| Year/Month | 1990/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | To evaluate the accuracy of PSP/LVESV as a detector of cornary artery disease, exercise radionuclide ventriculography was performed. In 26 patients with angina pectoris, the changes of LVEF, LVESV and PSP/LVESV were more sensitive for the detection of exercise-induced ischemia than the appearance of chest pain and the changes of ECG. In 112 patients with coronary artery disease and 55 subjects without coronary artery disease, the sensitivity, specificity, and overall accuracy of the change of PSP/LVESV were 96%, 98% and 96%, respectively. In present study, the sensitivity, specificity and overall accuracy of EF and LVESV were 96%, 91% and 95%, and 95%, 93% and 94%, respectively. Although the change of PSP/LVESV was considered to be the most usefull parameter, we can not detect the exercise-induced ischemia by these three global parameters in patients with coronary artery branch stenosis. In conclusion, diagnosis of coronary artery disease using radionuclide ventriculography should be performed using not only global LV parameters but also the regional indexes, such as regional wall motion, regional EF and other parameters. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc radionuclide ventriculography, ergometer exercise, coronary heart disease, peak systolic pressure/left ventricular end-systolic volume (PSP/LVESV). |
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