Japanese
Title上縦隔原発の好酸性細胞癌の1例
Subtitle《症例報告》
Authors津田隆俊*, 久保田昌宏*, 岩窪昭文*, 志藤光男*, 若林淳一**, 浅石和昭***, 森田和夫*
Authors(kana)
Organization*札幌医科大学放射線医学講座, **附属病院病理部, ***第一外科学講座
Journal核医学
Volume27
Number7
Page741-748
Year/Month1990/7
Article報告
Publisher日本核医学会
Abstract「要旨」縦隔原発甲状腺癌(好酸性細胞癌)の症例を報告する. 左頸部腫瘍を主訴とし, 頸部腫瘤の生検にて好酸性細胞癌の病理組織診断を受けた. 201Tl全身スキャンにて左頸部および右上縦隔に強い201Tlの集積を認めた. 胸部XPおよびX線CTでも右上縦隔に腫瘍陰影が認められた. 甲状腺微小癌のリンパ節転移が疑われ, 甲状腺左葉および右葉の摘出術が施行されたがその連続切片には腫瘤の所見はなかった. 縦隔腫瘍摘除術後の病理組織検査でも好酸性細胞癌と診断された. その後, 頸部リンパ節の腫脹, 骨転移, 癌性心外膜炎が出現した. 131I治療を検討したが転移病巣には放射性ヨードの集積を認めずその適応とはならなかった. 転移巣に対して放射線外照射治療, 化学療法が行なわれ, 一時的に腫瘍の縮小を見たが, 癌転移進行のため, 左頸部リンパ節腫脹出現後2年7か月後に死亡した.
Practice臨床医学：一般
KeywordsOxyphilic cell adenocarcinoma (Hurthle cell carcinoma), Tumor of Superior mediastinum, Aberrant thyroid cancer.
English
TitleA Case of Hurthle Cell Carcinoma in the Superior Mediastinum
Subtitle
AuthorsTakatoshi TSUDA*, Masahiro KUBOTA*, Akifumi IWAKUBO*, Mitsuo SHIDO*, Jun-ichi WAKABAYASHI**, Kazuaki ASAISHI***, Kazuo MORITA*
Authors(kana)
Organization*Department of Radiology, **Division of Clinical Pathology, ***First Department of Surgery, Sapporo Medical College
JournalThe Japanese Journal of nuclear medicine
Volume27
Number7
Page741-748
Year/Month1990/7
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractThis is a report for an unusual case of oxyphilic cell adenocarcinoma originating from anterior mediastinum in a 36-year-old male who complained of his neck lymphoadenopathy. 201Tl whole body scanning showed increased uptake of the left supraclavicular and upper mediastinal regions. There was no history of prior operation nor irradiation to the thyroid or neck region. Chest CT scanning also demonstrated the tumor in the superior mediastinum, but the mass has no increased 67Ga uptake. No tumor in the thyroid lobes was apparent on thyroid scintiscanning, ultrasonography and neck CT. The mediastinal tumor resection, the right and left thyroid lobectomy and the neck lymphonodectomy were completed. Serial sectioning of the resected thyroid lobes failed to show any tumorous tissue. The light microscopic features of a Hurthle-cell tumor arising in the mediastinal ectopic thyroid and diagnosed by neck lymph node biopsy were presented. The tumor was clinically malignant, having metastasized to the bone and the neck lymph nodes. Non surgical treatment including radioactive iodine (131I) therapy and combination chemotherapy were disappointing. The patient deteriorated progressively and died 16 months after thyroidectomy. We describe here an unusual case of a papillary growing and thyroglobulin producing tumor in the superior mediastinal region without evidence of a primary thyroid gland tumor.
PracticeClinical medicine
KeywordsOxyphilic cell adenocarcinoma (Hurthle cell carcinoma), Tumor of Superior mediastinum, Aberrant thyroid cancer.

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