| Japanese |
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| Title | 脳梗塞におけるremote effects - 123I-IMP SPECT study - |
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| Subtitle | 《原著》 |
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| Authors | 羽生春夫*, 新井久之*, 小林康孝*, 羽田野展由*, 勝沼英宇*, 鈴木孝成** |
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| Authors(kana) | |
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| Organization | *東京医科大学老年科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 6 |
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| Page | 629-638 |
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| Year/Month | 1990/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」一側中大脳動脈領域に限局した脳梗塞29例のremote effectについて, 123I-IMP SPECTを用い検討した. 一側大脳半球病変による対側小脳半球(crossed cerebellar diaschisis), 皮質下病変による患側皮質, 視放線の障害による同側後頭葉視覚領域, そして大脳皮質病変による患側視床へ及ぼす影響が本法による局所脳血流量の低下から確認された. これらは経神経的な抑制機序が推測されるが, diaschisisと共通の病態が考慮される可逆的現象のほかに, 慢性期に至るまで持続する不可逆的現象も少なくなく, その病態には変性過程を含む器質的病変の関与が推測された. また臨床症状との関連については必ずしも明らかでないことも少なくなかった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Remote effect, Diaschisis, Cerebral infarction, IMP, SPECT. |
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| English |
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| Title | Remote Effects in Cerebral Infarction - 123I-IMP SPECT Study - |
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| Subtitle | - Original Articles - |
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| Authors | Haruo HANYU*, Hisayuki ARAI*, Yasutaka KOBAYASHI*, Nobuyoshi HATANO*, Hideyo KATSUNUMA*, Takanari SUZUKI** |
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| Authors(kana) | |
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| Organization | *Department of Geriatric Medicine, **Department of Radiology, Tokyo Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 6 |
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| Page | 629-638 |
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| Year/Month | 1990/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We studied the remote effects in 29 patients with middle cerebral artery territory infarction by using single photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]iodoamphetamine. SPECT demonstrated a reduction in blood flow in the cerebellar hemisphere contralateral to the cerebral infarct, the cortex ipsilateral to the subcortical infarct, the visual cortex distal to the optic radiation lesion, and the thalamus ipsilateral to the cortical infarct. In addition to transient neuronal depression identified with diaschisis, our results indicated that persistent phenomena were apparently involved in these remote effects. The degenerative processes might be related to irreversible effects in remote areas. Clinical symptoms corresponding to the areas of hypoperfusion remote from infarcted lesions were not necessarily present. |
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| Practice | Clinical medicine |
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| Keywords | Remote effect, Diaschisis, Cerebral infarction, IMP, SPECT. |
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