| Japanese |
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| Title | Thallium-201心筋SPECTによる梗塞サイズ - 心室遅延電位の発生と空間分布との関連 - |
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| Subtitle | 《原著》 |
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| Authors | 中居賢司*, 伊藤忠一*, 盛合直樹*, 宮川朋久**, 青木英彦**, 鈴木智之**, 加藤邦彦***, 高橋恒男***, 柳沢融*** |
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| Organization | *岩手医科大学臨床検査医学, **第二内科, ***放射線科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 6 |
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| Page | 593-598 |
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| Year/Month | 1990/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」体表面加算心電図より得られる遅延電位(LP)は心筋梗塞に伴う持続性心室頻拍例(VT)に高頻度に認められ, VTの発生機序との関連から注目されている. 陳旧性心筋梗塞30例を対象とし, LPの有無, 空間分布とTl-201心筋SPECTで求めた心筋梗塞部位, サイズとの関連について検討した. 梗塞は各領域において正常群の平均-2標準偏差以下とし, 欠損部心筋量(DVR)を算出した. LPはX, Y, Z誘導加算心電図より, LPの空間分布は45誘導胸部単極加算心電図より判定した. LP陰性の前壁梗塞群のDVRは23±10%, LP陽性の前壁梗塞群では47±10%, LP陰性の下後壁梗塞群では18±8%, LP陽性の下後壁梗塞群では34±5%とLP陽性群で高値であった. また, LP陽性11例においてLPの空間分布は梗塞部位と関連があった. LPの発生には梗塞の大きさ, 梗塞部位も重要な要因と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 myocardial SPECT, Myocardial infarction, Signal-averaged ECG, Late potential. |
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| English |
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| Title | Relationship between the Occurrence of Late Potential and the Location and Size of Myocardial Infarction Evaluated by Thallium-201 SPECT |
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| Subtitle | - Original Articles - |
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| Authors | Kenji NAKAI*, Chuichi ITO*, Naoki MORIAI*, Tomohisa MIYAKAWA**, Hidehiko AOKI**, Tomoyuki SUZUKI**, Kunihiko KATO***, Tsuneo TAKAHASHI***, Toru YANAGISAWA** |
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| Authors(kana) | |
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| Organization | *Department of Clinical Pathology, **The Second Department of Internal Medicine, ***Department of Radiology, Iwate Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 6 |
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| Page | 593-598 |
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| Year/Month | 1990/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | High-frequency, low amplitude signals, late potentials (LPs), in the terminal portion of the body surface QRS of the signal-averaged ECG were frequently observed in ventricular tachycardia (VT) following myocardial infarction (MI). In this study, we evaluated the correlation between the occurrence of LPs and the size and location of MI estimated by Thallium-201 myocardial SPECT in 30 MI patients. The positive LPs were identified by the value of % RMS 40, the percent ratio of the root mean square voltage in the last 40 msec of the QRS complex to that of the total filtered QRS from the signal averaged ECG using bipolar X, Y, Z leads. The spatial distributions of LPs were evaluated by the LP30 area maps obtained by the body surface mapping using forty-five unipolar electrodes. Sixty projections were obtained over 180 degree by rotating gamma camera after 5 minutes intravenous injection of 74 MBq of Thallium-201. After low-pass filtering, images were reconstructed into short-axis, horizontal long-axis and vertical long-axis tomograms. The maximum count circumferential profiles for each short-axis cuts were generated from the apical to basal cut and they were expressed into two-dimensional polar functional maps (apex to the center), Bull's-eye map, to represent myocardial Tl distribution. Normal limits of myocardial Tl distribution were established as the mean minus 2 standard deviation from those of normal subjects. The MI size was estimated as defect volume ratio (DVR), the percent ratio of abnormal region to that of total volume of left ventricle. Significant differences in DVR were observed among MI with LPs and without LPs. The DVR was higher in MI with LPs (anterior MI: 47+-10%, inferior MI: 34+-5%) compared to that of MI without LPs (anterior MI: 23+-10%, inferior MI: 18+-8%). In all 11 cases with LPs, the spatial distribution of LPs were concordant with the MI locations in Bull's-eye maps. In conclusion, the size and location of MI may play a role for the occurrence of LPs. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 myocardial SPECT, Myocardial infarction, Signal-averaged ECG, Late potential. |
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