| Japanese |
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| Title | ジピリダモール負荷心筋シンチグラムのタリウムwashoutにおよぼすアミノフィリンの影響 |
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| Subtitle | 原著 |
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| Authors | 竹石恭知*, 殿岡一郎*, 目黒光彦*, 星光*, 政金生人*, 千葉純哉*, 阿部真也*, 駒谷昭夫**, 高橋和栄***, 立木楷*, 安井昭二* |
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| Authors(kana) | |
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| Organization | *山形大学医学部第一内科, **放射線科, ***附属病院放射線部 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 4 |
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| Page | 373-378 |
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| Year/Month | 1990/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 Control群 (有意冠動脈病変を認めない : C群) 28例と冠動脈疾患群 (1枝以上に50%以上の狭窄を有する : CAD群) 50例にジピリダモール負荷タリウム心筋シンチグラムを行った. C群のうちジピリダモール負荷の際にアミノフィリン (Am) を静注した12例 (C-Am (+) 群) の平均washout rate (WR) は, 静注しなかった16例 (C-Am (-) 群) よりも有意に大であった (42±5%vs. 35±7%, P<0.O1) . そこでWRの正常下限 (NL) を, Am静注の有無で別々に設定した. そしてC群全体からNLを設定した場合と別々に設定した場合で, CADの検出を行った. CAD検出のsensitivityはWRのNLをC群全体から設定した場合よりも, Amの有無で別々に設定した場合が高かった (84%vs. 92%) . 各冠動脈病変の検出は, sensitivity (80%vs. 86%), specificity (73%vs. 80%) , accuracy (78%vs. 85%) ともにAmの有無で別々にWRを標準化した場合が良好であった. Amを静注したCAD群はC-Am (+) 群から, 静注しないCAD群はC-Am (-) 群から別々にNLを設定したほうが, WRをより正確に評価することができ, 冠動脈病変検出の診断率も良好であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 scintigraphy, Washout rate, Dipyridamole, Aminophylline |
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| English |
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| Title | Effect of Aminophylline on Thallium-201 Washout Rate during Myocardial Perfusion Imaging with Dipyridamole |
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| Authors | Yasuchika TAKEISHI*, Ichiro TONO-OKA*, Mitsuhiko MEGURO*, Hikaru HOSHI*, Ikuto MASAKANE*, Junya CHIBA*, Shinya ABE*, Akio KOMATANI**, Kazuei TAKAHASHI***, Kai TSUIKI*, Shoji YASUI* |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, **Department of Radiology, Yamagata University school of Medicine, ***Department of Radiology, Yamagata University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 4 |
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| Page | 373-378 |
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| Year/Month | 1990/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Thallium-201 myocardial perfusion imaging with dipyridamole was performed on 78 patients (pts) with suspected coronary artery disease (CAD) . Twenty eight pts had normal coronary arteries (control group) , and 50 pts had 50% or greater stenosis in one or more major Coronary arteries (CAD group) . In control group, aminophylline (Am) was infused intravenously on 12 pts during dipyridamole testing. Mean washout rate (WR) of these l2 pts was greater than that of 16 pts without Am (42%vs35%, p<0.01) . Then normal limit of WR was defined separately from the pts of control group with and without Am. The sensitivity for detecting the pts with CAD by WR analysis which normal limit was calculated separately with and without Am was 92% (46/50) . When normal limit of WR was determined from all pts in control group, the sensitivity decreased to 84% (42/50) . Am significantly affected thallium-201 washout during dipyridamole testing. WR of CAD pts should be estimated by specific set of normal limit with and without Am. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 scintigraphy, Washout rate, Dipyridamole, Aminophylline |
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