Japanese
TitleI-123IMP脳血流SPECTにおける画質と病変検出率の検討
Subtitle原著
Authors蓑島聡1, 安西好美1, 内田佳孝1, 宇野公一1, 伊丹純1, 有水昇1, 町田喜久雄2, 本田憲業2, 松本徹3, 飯沼武3, 油井信春4, 川上憲司5, 久保敦司6, 村田啓7, 石井勝己8, 小山田日吉丸9, 中島哲夫10
Authors(kana)
Organization1千葉大学医学部放射線科, 2埼玉医科大学総合医療センター放射線科, 3放射線医学総合研究所臨床研究部, 4千葉県がんセンター核医学科, 5慈恵医科大学放射線科, 6慶應大学医学部放射線科, 7虎ノ門共済病院放射線科, 8北里医科大学放射線科, 9癌研究会附属病院アイソトープ部, 10埼玉県がんセンター放射線科
Journal核医学
Volume27
Number4
Page323-332
Year/Month1990/4
Article原著
Publisher日本核医学会
Abstract「要旨」 I-123IMP脳血流SPECT画像の画質を視覚的に分類し病変検出率と比較することにより, 画質が病変検出に及ぼす影響について検討を行った. I-123IMP静注後30分以内に撮像を開始した42症例のフィルム上のSPECT画像で, 明らかにI-123IMPが集積低下をきたすと考えられた59病変を対象とした. 各病変の検出率はX線CTを参考にした14人の放射線科医の読影結果より求めた. SPECT画像の画質は, 大脳皮質集積, 後頭葉視覚皮質分離, 白質集積, 基底核・視床分離, 基底核・視床濃度の5項目をおのおの視覚的に2段階に分類し評価した. その結果, 大脳1葉に留まる病変, 白質病変, 基底核・視床病変など病変検出率の低い深部病変, 小病変において, その病変検出率が画質に影響されることが判明した. また考案したI-123IMP SPECT画像の視覚的画質分類は, 病変検出率という観点から画質分類を行う上で有用な方法であると考えられた.
Practice臨床医学：一般
KeywordsN-isopropyl-p [123I] iodoamphetamine, SPECT, Lesion detection, Image quality, Cerebrovascular disorder
English
TitleEvaluation of Image Quality and Lesion Detectability on I-123IMP Brain SPECT
SubtitleOriginal Articles
AuthorsSatoshi MINOSHIMA1, Yoshimi ANZAI1, Yoshitaka UCHIDA1, Kimiichi UNO1, Jun ITAMI1, Noboru ARIMIZU1, Kikuo MACHIDA2, Norinari HONDA2, Tohru MATSUMOTO3, Takeshi IINUMA3, Nobuharu YUI4, Kenji KAWAKAMI5, Atsushi KUBO6, Hajime MURATA7, Katsumi ISHII8, Hiyoshimaru OYAMADA9, Tetsuo NAKAJIMA10
Authors(kana)
Organization1Department of Radiology, School of Medicine, Chiba University, 2Department of Radiology, Saitama Medical Center, Saitama Medical School, 3Division of Clinical Research, National Institute of Radiological Sciences, 4Department of Nuclear Medicine, Chiba Prefectural Cancer Center, 5Department of Radiology, Jikei University School of Medicine, 6Department of Radiology, School of Medicine, Keio University, 7Deparyment of Radiology, Tranomon Kyosai Hospital, 8Department of Radiology, School of Medicine, Kitasato University, 9Department of Nuclear Medicine, Cancer Institute Hospital, 10Department of Radiology, Saitama Prefectural Cancer Center
JournalThe Japanese Journal of nuclear medicine
Volume27
Number4
Page323-332
Year/Month1990/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Influence of image quality on lesion detectability in I-123 IMP brain SPECT was discussed in fortytwo cases with various cerebrovascular disorders. Fifty nine lesions, which were considered to show decreased uptake of I-123IMP, were analyzed in this study. In all cases, SPECT examinations were started within 30 minutes after intravenous administration of 3 mCi of I-123IMP. To determine the lesion detectability, fourteen radiologists from nine hospitals were gathered and film reading was carried out. To classify the image quality into valuable or not, findings of five points on SPECT image were visually evaluated ; 1) uniformity of cortex accumulation, 2) separation of bilateral visual cortices, 3) density of white matter, 4) separation between basal ganglion and thalamus, 5) density of basal ganglion and thalamus. Mean lesion detections were 10.3/14 for the lesions of cerebral cortex, 9 for cerebellum, 3.58 for white matter and 3.22 for basal ganglion and thalamus, respectively. The detectability was certainly influenced by the image quality in the lesion of basal ganglion and thalamus, white matter and single lobe of cerebral cortex. We concluded that detection of small lesions and deep lesions with I-123IMP SPECT was dependent on the image quality and the proposed classification of I-123IMP SPECT image was useful for evaluating image quality from the points of view of the lesion detectability.
PracticeClinical medicine
KeywordsN-isopropyl-p [123I] iodoamphetamine, SPECT, Lesion detection, Image quality, Cerebrovascular disorder

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